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TSTD3 thiosulfate sulfurtransferase like domain containing 3 [ Homo sapiens (human) ]

Gene ID: 100130890, updated on 8-Mar-2024

Summary

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Official Symbol
TSTD3provided by HGNC
Official Full Name
thiosulfate sulfurtransferase like domain containing 3provided by HGNC
Primary source
HGNC:HGNC:40910
See related
Ensembl:ENSG00000279170 AllianceGenome:HGNC:40910
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in testis (RPKM 1.4), prostate (RPKM 1.1) and 25 other tissues See more
Orthologs
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Genomic context

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See TSTD3 in Genome Data Viewer
Location:
6q16.2
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (99424906..99586256)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (100599236..100761214)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (99968925..99981061)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:99793932-99794432 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:99794433-99794933 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:99795824-99796388 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17414 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17415 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17416 Neighboring gene failed axon connections homolog, metaxin like GST domain containing Neighboring gene MPRA-validated peak5980 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:99841327-99841966 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:99849871-99851070 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:99872987-99874186 Neighboring gene NANOG hESC enhancer GRCh37_chr6:99904596-99905315 Neighboring gene coenzyme Q3, methyltransferase Neighboring gene PNISR antisense RNA 1 Neighboring gene PNN interacting serine and arginine rich protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17417 Neighboring gene ubiquitin specific peptidase 45 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:99962307-99963214 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:99963215-99964120 Neighboring gene uncharacterized LOC124901365 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24857 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24858 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24859 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24860 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24861 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24862 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:100023517-100023714 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24863 Neighboring gene CCNC and PRDM13 intergenic region DNase I hypersensitve site DHS6S1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17421 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:100051429-100052268 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17423 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:100061850-100062398 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17422 Neighboring gene cyclin C Neighboring gene ribosomal protein S3 pseudogene 5 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:100097329-100097949 Neighboring gene PR/SET domain 13 Neighboring gene Sharpr-MPRA regulatory region 7231 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:100271711-100272281 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:100379521-100380020 Neighboring gene melanin concentrating hormone receptor 2 Neighboring gene MCHR2 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Homology

Clone Names

  • DKFZp781B0241

General protein information

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Preferred Names
thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3
Names
rhodanese domain-containing protein 3
thiosulfate sulfurtransferase (rhodanese)-like domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195131.2 → NP_001182060.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3

    See identical proteins and their annotated locations for NP_001182060.1

    Status: VALIDATED

    Source sequence(s)
    AL137784, DN996863
    Consensus CDS
    CCDS83109.1
    UniProtKB/Swiss-Prot
    H0UI37
    Related
    ENSP00000489733.1, ENST00000452647.3
    Conserved Domains (1) summary
    cl00125
    Location:30 → 96
    RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    99424906..99586256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_007059188.1 RNA Sequence

  2. XR_001743062.3 RNA Sequence

  3. XR_007059189.1 RNA Sequence

  4. XR_001743060.3 RNA Sequence

  5. XR_007059190.1 RNA Sequence

  6. XR_001743061.3 RNA Sequence

  7. XR_007059191.1 RNA Sequence

  8. XR_001743064.3 RNA Sequence

  9. XR_007059187.1 RNA Sequence

  10. XR_007059186.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    100599236..100761214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054353970.1 → XP_054209945.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    H0UI37

  2. XM_054353968.1 → XP_054209943.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    H0UI37

  3. XM_054353969.1 → XP_054209944.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    H0UI37

  4. XM_054353967.1 → XP_054209942.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    H0UI37

  5. XM_054353966.1 → XP_054209941.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    H0UI37

  6. XM_054353965.1 → XP_054209940.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    H0UI37

  7. XM_054353964.1 → XP_054209939.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    H0UI37

RNA

  1. XR_008487228.1 RNA Sequence

  2. XR_008487227.1 RNA Sequence

  3. XR_008487229.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
H0UI37.1 GenPept UniProtKB/Swiss-Prot:H0UI37

Gene LinkOut

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