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FAM83A-AS1 FAM83A antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 100131726, updated on 31-Mar-2024

Summary

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Official Symbol
FAM83A-AS1provided by HGNC
Official Full Name
FAM83A antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:48658
See related
Ensembl:ENSG00000204949 AllianceGenome:HGNC:48658
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HCCC11; HCCC11_v1; HCCC11_v2
Expression
Biased expression in esophagus (RPKM 3.1), liver (RPKM 1.6) and 2 other tissues See more
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Genomic context

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Location:
8q24.13
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (123201172..123202743, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (124332308..124333879, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (124213412..124214983, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 31 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19494 Neighboring gene tRNA-Met (anticodon CAT) 1-1 Neighboring gene Sharpr-MPRA regulatory region 4427 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:124186535-124187034 Neighboring gene small nucleolar RNA U3 Neighboring gene family with sequence similarity 83 member A Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:124209501-124210245 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:124219477-124220229 Neighboring gene ZHX1-C8orf76 readthrough Neighboring gene microRNA 4663 Neighboring gene chromosome 8 open reading frame 76 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LncRNA FAM83A-AS1 promotes epithelial-mesenchymal transition of pancreatic cancer cells via Hippo pathway. Wang H, et al. Cell Cycle, 2023 Jun. PMID 37245082,
  2. FAM83A antisense RNA 1 (FAM83A-AS1) silencing impairs cell proliferation and induces autophagy via MET-AMPKɑ signaling in lung adenocarcinoma. Zhao H, et al. Bioengineered, 2022 May. PMID 35635086, Free PMC Article
  3. FAM83A-AS1 promotes lung adenocarcinoma cell migration and invasion by targeting miR-150-5p and modifying MMP14. Xiao G, et al. Cell Cycle, 2019 Nov. PMID 31522616, Free PMC Article
  4. Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression. Huang H, et al. Bioengineered, 2022 Mar. PMID 35164653, Free PMC Article
  5. LncRNA FAM83A-AS1 promotes lung adenocarcinoma progression by enhancing the pre-mRNA stability of FAM83A. Wang W, et al. Thorac Cancer, 2021 May. PMID 33687144, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sense and anti-sense: Role of FAM83A and FAM83A-AS1 in Wnt, EGFR, PI3K, EMT pathways and tumor progression.
    Title: Sense and anti-sense: Role of FAM83A and FAM83A-AS1 in Wnt, EGFR, PI3K, EMT pathways and tumor progression.
  2. LncRNA FAM83A-AS1 promotes epithelial-mesenchymal transition of pancreatic cancer cells via Hippo pathway.
    Title: LncRNA FAM83A-AS1 promotes epithelial-mesenchymal transition of pancreatic cancer cells via Hippo pathway.
  3. High-risk pathological subtype associated FAM83A-AS1 promotes malignancy and glycolysis of lung adenocarcinoma via miR-202-3p/HK2 axis.
    Title: High‑risk pathological subtype associated FAM83A‑AS1 promotes malignancy and glycolysis of lung adenocarcinoma via miR‑202‑3p/HK2 axis.
  4. FAM83A antisense RNA 1 (FAM83A-AS1) silencing impairs cell proliferation and induces autophagy via MET-AMPKa signaling in lung adenocarcinoma.
    Title: FAM83A antisense RNA 1 (FAM83A-AS1) silencing impairs cell proliferation and induces autophagy via MET-AMPKɑ signaling in lung adenocarcinoma.
  5. Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression.
    Title: Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression.
  6. LncRNA FAM83A-AS1 promotes lung adenocarcinoma progression by enhancing the pre-mRNA stability of FAM83A.
    Title: LncRNA FAM83A-AS1 promotes lung adenocarcinoma progression by enhancing the pre-mRNA stability of FAM83A.
  7. LncRNA FAM83A-AS1 aggravates the malignant development of esophageal cancer by binding to miR-495-3p.
    Title: LncRNA FAM83A-AS1 aggravates the malignant development of esophageal cancer by binding to miR-495-3p.
  8. FAM83A-AS1 promotes lung adenocarcinoma cell migration and invasion by targeting miR-150-5p and modifying MMP14.
    Title: FAM83A-AS1 promotes lung adenocarcinoma cell migration and invasion by targeting miR-150-5p and modifying MMP14.
  9. LncRNA FAM83A-AS1 promotes lung adenocarcinoma by increasing FAM83A expression.
    Title: Long noncoding antisense RNA FAM83A-AS1 promotes lung cancer cell progression by increasing FAM83A.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • HCC-related HCC-C11_v3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024479.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AY211907
    Related
    ENST00000517519.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    123201172..123202743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    124332308..124333879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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