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igf2 insulin like growth factor 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100134992, updated on 8-Mar-2024

Summary

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Official Symbol
igf2provided by Xenbase
Official Full Name
insulin like growth factor 2provided by Xenbase
Primary source
Xenbase:XB-GENE-482586
See related
Ensembl:ENSXETG00000048204
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
igf-2; IGF-II; igf2-a; igf2-b; insigf; pp9974
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
5
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (21969660..22010683)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (12727882..12768659)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene general transcription factor II-I repeat domain-containing protein 2 Neighboring gene mitochondrial ribosomal protein L23 Neighboring gene insulin Neighboring gene tyrosine hydroxylase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
  
enables hormone activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
insulin-like growth factor II
Names
insulin-like growth factor 2 (somatomedin A)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113672.1 → NP_001107144.1  insulin-like growth factor II precursor

    See identical proteins and their annotated locations for NP_001107144.1

    Status: PROVISIONAL

    Source sequence(s)
    BC155999
    UniProtKB/TrEMBL
    A0A803JAK2, A9JSC3
    Related
    ENSXETP00000104916.1, ENSXETT00000121352.1
    Conserved Domains (2) summary
    cd04368
    Location:24 → 88
    IlGF; IlGF, insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On ...
    pfam08365
    Location:115 → 170
    IGF2_C; Insulin-like growth factor II E-peptide

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    21969660..22010683
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012960554.3 → XP_012816008.1  insulin-like growth factor II isoform X1

    UniProtKB/TrEMBL
    A0A803JAK2, A0A803K087
    Related
    ENSXETP00000106613.1, ENSXETT00000115620.1
    Conserved Domains (2) summary
    cd04368
    Location:59 → 123
    IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...
    pfam08365
    Location:150 → 205
    IGF2_C; Insulin-like growth factor II E-peptide

  2. XM_012960555.3 → XP_012816009.1  insulin-like growth factor II isoform X2

    UniProtKB/TrEMBL
    A0A803JAK2, A0A8J0SJ94
    Conserved Domains (2) summary
    cd04368
    Location:59 → 123
    IlGF; IlGF, insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On ...
    pfam08365
    Location:149 → 204
    IGF2_C; Insulin-like growth factor II E-peptide
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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