anos1 anosmin 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: anos1provided by Xenbase
Official Full Name: anosmin 1provided by Xenbase
Primary source: Xenbase:XB-GENE-488217
See related: Ensembl:ENSXETG00000022299
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: hha; kal; kms; kal1; admlx; kalig-1
Orthologs: human all
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Genomic context

Location:: chromosome: 2

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	2	NC_030678.2 (36297415..36413433)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	2	NC_030678.1 (28706250..28821041)

Chromosome 2 - NC_030678.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These findings indicate that anos1 has a conserved function in the development of craniofacial structures, and indicate that anos1-depleted Xenopus embryos represent a useful model to analyze the pathogenesis of Kallmann syndrome.
Title: Anosmin-1 is essential for neural crest and cranial placodes formation in Xenopus.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables peptidase inhibitor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: anosmin-1

Names: Kallmann syndrome 1 sequence

NP_001107160.1

EC 3.4.21.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113688.1 → NP_001107160.1 anosmin-1 precursor

See identical proteins and their annotated locations for NP_001107160.1

Status: PROVISIONAL

Source sequence(s)

BC155677

UniProtKB/TrEMBL

A9JRI8

Related

ENSXETP00000055036.3, ENSXETT00000055036.4

Conserved Domains (4) summary

smart00217
Location:135 → 181

WAP; Four-disulfide core domains

cd00063
Location:295 → 386

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:553 → 647

fn3; Fibronectin type III domain

pfam17869
Location:49 → 130

Cys_box; Anosmin cysteine rich domain