U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tnca tenascin Ca [ Danio rerio (zebrafish) ]

Gene ID: 100149028, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
tncaprovided by ZNC
Official Full Name
tenascin Caprovided by ZNC
Primary source
ZFIN:ZDB-GENE-130530-849
See related
Ensembl:ENSDARG00000078362 AllianceGenome:ZFIN:ZDB-GENE-130530-849
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zmp:0000000846
Summary
Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; autosomal dominant nonsyndromic deafness 56; and pulmonary hypertension. Orthologous to human TNC (tenascin C). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tnca in Genome Data Viewer
Location:
chromosome: 5
Exon count:
29
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (5707991..5830978, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (5215721..5338956, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene RAB, member RAS oncogene family-like 6a Neighboring gene TNF receptor-associated factor 2-like Neighboring gene uncharacterized protein PB18E9.04c-like Neighboring gene uncharacterized LOC110439801 Neighboring gene zgc:73226

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tenascin-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    5707991..5830978 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476382.1 → XP_021332057.1  tenascin-like isoform X1

    UniProtKB/TrEMBL
    A0A8M9PKQ8
    Conserved Domains (4) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2114 → 2323
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain
    pfam00041
    Location:2023 → 2096
    fn3; Fibronectin type III domain

  2. XM_021476383.1 → XP_021332058.1  tenascin-like isoform X2

    UniProtKB/TrEMBL
    A0A8M9PY97
    Conserved Domains (4) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1857 → 2066
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain
    pfam00041
    Location:1766 → 1839
    fn3; Fibronectin type III domain

  3. XM_021476385.1 → XP_021332060.1  tenascin-like isoform X4

    UniProtKB/TrEMBL
    A0A8M9QEF6
    Conserved Domains (4) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1659 → 1868
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain
    pfam00041
    Location:1568 → 1641
    fn3; Fibronectin type III domain

  4. XM_021476384.1 → XP_021332059.1  tenascin-like isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q3W9
    Conserved Domains (4) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1750 → 1959
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain
    pfam00041
    Location:1659 → 1732
    fn3; Fibronectin type III domain

  5. XM_009301159.3 → XP_009299434.1  tenascin-like isoform X6

    UniProtKB/TrEMBL
    A0A8M3B253
    Conserved Domains (4) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1402 → 1611
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam00041
    Location:1311 → 1388
    fn3; Fibronectin type III domain
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain

  6. XM_009301158.3 → XP_009299433.1  tenascin-like isoform X5

    UniProtKB/TrEMBL
    A0A8M3AS32
    Conserved Domains (4) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1493 → 1702
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam00041
    Location:1402 → 1479
    fn3; Fibronectin type III domain
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain

  7. XM_009301160.3 → XP_009299435.1  tenascin-like isoform X7

    UniProtKB/TrEMBL
    A0A8M3AZ84, E7EZJ2
    Related
    ENSDARP00000098154.4, ENSDART00000112856.4
    Conserved Domains (4) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1310 → 1519
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam00041
    Location:1219 → 1296
    fn3; Fibronectin type III domain
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain

  8. XM_021476388.1 → XP_021332063.1  tenascin-like isoform X8

    UniProtKB/TrEMBL
    A0A8M9PKR5
    Conserved Domains (3) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain
    pfam00041
    Location:772 → 852
    fn3; Fibronectin type III domain

  9. XM_021476387.1 → XP_021332062.1  tenascin-like isoform X8

    UniProtKB/TrEMBL
    A0A8M9PKR5
    Conserved Domains (3) summary
    cd00063
    Location:862 → 947
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07974
    Location:316 → 341
    EGF_2; EGF-like domain
    pfam00041
    Location:772 → 852
    fn3; Fibronectin type III domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases