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Mup19 major urinary protein 19 [ Mus musculus (house mouse) ]

Gene ID: 100189605, updated on 8-Feb-2024

Summary

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Official Symbol
Mup19provided by MGI
Official Full Name
major urinary protein 19provided by MGI
Primary source
MGI:MGI:3705235
See related
Ensembl:ENSMUSG00000078673 AllianceGenome:MGI:3705235
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mup6; Mup8; Mup11; Mup14; Mup17; Gm12552; 100039247
Summary
Is expressed in liver. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward liver adult (RPKM 2730.8) See more
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Genomic context

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See Mup19 in Genome Data Viewer
Location:
4 B3; 4 32.9 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (61696561..61700597, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (61778324..61782355, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene major urinary protein, pseudogene 15 Neighboring gene major urinary protein 18 Neighboring gene major urinary protein, pseudogene 16 Neighboring gene STARR-seq mESC enhancer starr_10399 Neighboring gene major urinary protein 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Analysis of mouse major urinary protein genes: variation between the exonic sequences of group 1 genes and a comparison with an active gene out with group 1 both suggest that gene conversion has occurred between MUP genes. Clark AJ, et al. EMBO J, 1985 Dec 1. PMID 3004936, Free PMC Article
  2. Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver. Jiang J, et al. J Biol Chem, 2017 Apr 21. PMID 28258223, Free PMC Article
  3. Species specificity in major urinary proteins by parallel evolution. Logan DW, et al. PLoS One, 2008 Sep 25. PMID 18815613, Free PMC Article
  4. Identification of protein pheromones that promote aggressive behaviour. Chamero P, et al. Nature, 2007 Dec 6. PMID 18064011
  5. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Charkoftaki G, et al. Hum Genomics, 2019 Feb 19. PMID 30782214, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
major urinary protein 11
Names
Alpha-2U-globulin
Group 1, BS6
MUP 6
MUP11 and MUP8
Major urinary protein 6
Major urinary proteins 11 and 8
major urinary protein 14
major urinary protein 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135127.2 → NP_001128599.1  major urinary protein 11 precursor

    See identical proteins and their annotated locations for NP_001128599.1

    Status: VALIDATED

    Source sequence(s)
    AK013259
    Consensus CDS
    CCDS51200.1
    UniProtKB/Swiss-Prot
    P02762, P11589, P70119, Q78EF5, Q91V46, Q99JF6
    UniProtKB/TrEMBL
    A2CGB6, B5TE76
    Related
    ENSMUSP00000079442.3, ENSMUST00000080606.9
    Conserved Domains (1) summary
    cd19428
    Location:23 → 180
    lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    61696561..61700597 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537526.5 → XP_006537589.1  major urinary protein 11 isoform X1

    See identical proteins and their annotated locations for XP_006537589.1

    UniProtKB/TrEMBL
    A9C496
    Conserved Domains (1) summary
    cd19428
    Location:23 → 172
    lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

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