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slc34a1a solute carrier family 34 member 1a [ Danio rerio (zebrafish) ]

Gene ID: 100329340, updated on 27-Mar-2024

Summary

Official Symbol
slc34a1aprovided by ZNC
Official Full Name
solute carrier family 34 member 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-101006-3
See related
Ensembl:ENSDARG00000028824 AllianceGenome:ZFIN:ZDB-GENE-101006-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
npt2a
Summary
Predicted to enable sodium:phosphate symporter activity. Predicted to be involved in cellular phosphate ion homeostasis and sodium-dependent phosphate transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in apical plasma membrane; brush border; and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Fanconi syndrome (multiple); chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis. Orthologous to human SLC34A1 (solute carrier family 34 member 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (836011..859237, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (818021..840763, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 35-27 Neighboring gene adrenergic, alpha-2D-, receptor a Neighboring gene si:ch73-302a4.4 Neighboring gene regulator of G protein signaling 14a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables sodium:phosphate symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sodium:phosphate symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in intracellular phosphate ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in sodium-dependent phosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within sodium-dependent phosphate transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in brush border IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
sodium-dependent phosphate transport protein 2A
Names
solute carrier family 34 (sodium phosphate), member 1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    836011..859237 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002664258.6XP_002664304.2  sodium-dependent phosphate transport protein 2A

    UniProtKB/TrEMBL
    A0A8M1RDZ0, F8W579
    Related
    ENSDARP00000123760.1, ENSDART00000148687.3
    Conserved Domains (2) summary
    TIGR01013
    Location:87581
    2a58; Phosphate:Na+ Symporter (PNaS) Family
    pfam02690
    Location:89179
    Na_Pi_cotrans; Na+/Pi-cotransporter