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slc2a3b solute carrier family 2 member 3b [ Danio rerio (zebrafish) ]

Gene ID: 100330897, updated on 11-Apr-2024

Summary

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Official Symbol
slc2a3bprovided by ZNC
Official Full Name
solute carrier family 2 member 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-121031-5
See related
Ensembl:ENSDARG00000037861 AllianceGenome:ZFIN:ZDB-GENE-121031-5
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable transmembrane transporter activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in brain. Orthologous to human SLC2A3 (solute carrier family 2 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
chromosome: 16
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (12477660..12496816, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (12586882..12605207, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene si:dkey-26c10.5 Neighboring gene transient receptor potential cation channel, subfamily V, member 6 Neighboring gene eph receptor B6 Neighboring gene cytochrome c oxidase subunit 6B2 Neighboring gene Ras interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Glucose metabolism is required for oocyte maturation of zebrafish. Kang T, et al. Biochem Biophys Res Commun, 2021 Jun 25. PMID 33945997
  2. Transcript Analysis of Zebrafish GLUT3 Genes, slc2a3a and slc2a3b, Define Overlapping as Well as Distinct Expression Domains in the Zebrafish (Danio rerio) Central Nervous System. Lechermeier CG, et al. Front Mol Neurosci, 2019. PMID 31507372, Free PMC Article
  3. Expansion of transducin subunit gene families in early vertebrate tetraploidizations. Lagman D, et al. Genomics, 2012 Oct. PMID 22814267
  4. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article
  5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables D-glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate transport IEA
Inferred from Electronic Annotation
more info
  
involved_in dehydroascorbic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glucose import IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to insulin IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
solute carrier family 2, facilitated glucose transporter member 3
Names
solute carrier family 2 (facilitated glucose transporter), member 3b
unm_sa704

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    12477660..12496816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002667123.5 → XP_002667169.2  solute carrier family 2, facilitated glucose transporter member 3

    UniProtKB/TrEMBL
    A0A8M1RS38, F1R1M7, X1WBX2
    Related
    ENSDARP00000008780.8, ENSDART00000019941.10
    Conserved Domains (2) summary
    cd06174
    Location:66 → 479
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:19 → 494
    Sugar_tr; Sugar (and other) transporter
Nucleotide Protein Strain
Heading Accession and Version

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