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slc44a1a solute carrier family 44 member 1a [ Danio rerio (zebrafish) ]

Gene ID: 100333377, updated on 11-Apr-2024

Summary

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Official Symbol
slc44a1aprovided by ZNC
Official Full Name
solute carrier family 44 member 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-204
See related
Ensembl:ENSDARG00000015946 AllianceGenome:ZFIN:ZDB-GENE-050417-204
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
slc44a1; zgc:112201
Summary
Predicted to enable transmembrane transporter activity. Acts upstream of or within sensory perception of sound. Predicted to be integral component of membrane. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to several human genes including SLC44A1 (solute carrier family 44 member 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 1
Exon count:
16
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (52633163..52653608)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (51998436..52017719)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene aprataxin Neighboring gene oxysterol binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. SLC44A4 mutation causes autosomal dominant hereditary postlingual non-syndromic mid-frequency hearing loss. Ma Z, et al. Hum Mol Genet, 2017 Jan 15. PMID 28013291
  2. Gene Expression of CRAL_TRIO Family Proteins modulated by Vitamin E Deficiency in Zebrafish (Danio Rerio). Watt AT, et al. J Nutr Biochem, 2021 Nov. PMID 34119630, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within sensory perception of sound IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
choline transporter-like protein 1
Names
cdw92
solute carrier family 44 (choline transporter), member 1a
solute carrier family 44, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    52633163..52653608
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002660581.6 → XP_002660627.2  choline transporter-like protein 1

    UniProtKB/TrEMBL
    A0A8M1RH24, F1Q9M4
    Related
    ENSDARP00000007186.9, ENSDART00000011725.10
    Conserved Domains (1) summary
    pfam04515
    Location:288 → 600
    Choline_transpo; Plasma-membrane choline transporter
Nucleotide Protein Strain
Heading Accession and Version

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