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PFKM phosphofructokinase, muscle [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100345647, updated on 3-Apr-2024

Summary

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Gene symbol
PFKM
Gene description
phosphofructokinase, muscle
See related
Ensembl:ENSOCUG00000017445
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
PFK; PFK-A; PFK-M; ATP-PFK
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 8 NC_067381.1 (111767301..111801291)

Chromosome 8 - NC_067381.1Genomic Context describing neighboring genes Neighboring gene serine/arginine repetitive matrix protein 2 Neighboring gene collagen type II alpha 1 chain Neighboring gene SUMO specific peptidase 1 Neighboring gene ankyrin repeat and SOCS box containing 8 Neighboring gene coiled-coil domain containing 184

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067381.1 Chromosome 8 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism. Šmerc A, et al. PLoS One, 2011 May 4. PMID 21573193, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Posttranslational modification of PFK1 enzyme might be the pivotal factor of deregulated glycolytic flux in tumors.
    Title: Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables AMP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-6-phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monosaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical glycolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose 1,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructokinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent 6-phosphofructokinase, muscle type
Names
6-phosphofructokinase type A
Phosphofructo-1-kinase isozyme A
Phosphohexokinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067381.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    111767301..111801291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051850440.1 → XP_051706400.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

  2. XM_051850433.1 → XP_051706393.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X1

    UniProtKB/TrEMBL
    A0A5F9DGX0

  3. XM_051850434.1 → XP_051706394.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X2

  4. XM_051850436.1 → XP_051706396.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

  5. XM_051850438.1 → XP_051706398.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

  6. XM_051850437.1 → XP_051706397.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

  7. XM_051850435.1 → XP_051706395.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

  8. XM_051850439.1 → XP_051706399.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00511.3 GenPept UniProtKB/Swiss-Prot:P00511

Gene LinkOut

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