LOC100360087 ferritin light chain 1-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: LOC100360087provided by RGD
Full Name: ferritin light chain 1-likeprovided by RGD
Primary source: RGD:2322860
See related: AllianceGenome:RGD:2322860
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ftl1
Summary: Predicted to enable iron ion binding activity. Predicted to be involved in iron ion transport. Predicted to be part of intracellular ferritin complex. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndrome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 5q36

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (151606496..151607413)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (146322749..146323666)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (152325852..152326798)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Ftl1 (e-PCR), detects polymorphism
- UniSTS:532424

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ferric iron binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in iron ion transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of intracellular ferritin complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ferritin light chain 1

Names: ferritin L subunit 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001419555.1 → NP_001406484.1 ferritin light chain 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000005

UniProtKB/Swiss-Prot

P02793, Q6P7T1

UniProtKB/TrEMBL

A6JB33