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Zfp729b zinc finger protein 729b [ Mus musculus (house mouse) ]

Gene ID: 100416706, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp729bprovided by MGI
Official Full Name
zinc finger protein 729bprovided by MGI
Primary source
MGI:MGI:2145180
See related
Ensembl:ENSMUSG00000058093 AllianceGenome:MGI:2145180
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and negative regulation of transposon integration. Predicted to be located in nucleus. Orthologous to human ZNF91 (zinc finger protein 91). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 1.6), CNS E18 (RPKM 1.4) and 23 other tissues See more
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Genomic context

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See Zfp729b in Genome Data Viewer
Location:
13 B3; 13 34.59 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67737558..67757767, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (67589439..67609707, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 748 Neighboring gene RIKEN cDNA 9430065F17 gene Neighboring gene STARR-positive B cell enhancer ABC_E9881 Neighboring gene STARR-positive B cell enhancer ABC_E4077 Neighboring gene STARR-seq mESC enhancer starr_34905 Neighboring gene zinc finger protein 729a Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:67738709-67738896 Neighboring gene predicted gene, 46439

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Potential readthrough

Included genes: Zfp87, Zfp58

Homology

Clone Names

  • MGC54886

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein
Names
Novel C2H2 type zinc finger protein (AA987161)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163246.3 → NP_001156718.1  zinc finger protein isoform 1

    See identical proteins and their annotated locations for NP_001156718.1

    Status: VALIDATED

    Source sequence(s)
    CT573016
    Consensus CDS
    CCDS56892.1
    UniProtKB/TrEMBL
    Q80VN4
    Related
    ENSMUSP00000012873.9, ENSMUST00000012873.16
    Conserved Domains (5) summary
    smart00349
    Location:5 → 63
    KRAB; krueppel associated box
    COG5048
    Location:466 → 879
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:778 → 798
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:5 → 44
    KRAB; KRAB box
    pfam13465
    Location:482 → 505
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001401859.1 → NP_001388788.1  zinc finger protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT573016

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    67737558..67757767 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_019411.1: Suppressed sequence

    Description
    NG_019411.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version

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