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MIR3927 microRNA 3927 [ Homo sapiens (human) ]

Gene ID: 100500898, updated on 10-Oct-2023

Summary

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Official Symbol
MIR3927provided by HGNC
Official Full Name
microRNA 3927provided by HGNC
Primary source
HGNC:HGNC:38901
See related
Ensembl:ENSG00000263861 miRBase:MI0016435; AllianceGenome:HGNC:38901
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See MIR3927 in Genome Data Viewer
Location:
9q31.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (109511475..109511545, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (121680863..121680933, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (112273755..112273825, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene erythrocyte membrane protein band 4.1 like 4B Neighboring gene RNA, U6 small nuclear 984, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20165 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20166 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20167 Neighboring gene MT-ND2 pseudogene 11 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28759 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28760 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28764 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28763 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28762 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28761 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28765 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:112193017-112193518 Neighboring gene protein tyrosine phosphatase non-receptor type 3 Neighboring gene Sharpr-MPRA regulatory region 2753 Neighboring gene HNF1 motif-containing MPRA enhancer 98 Neighboring gene Y-box binding protein 1 pseudogene 6 Neighboring gene PALM2 and AKAP2 fusion Neighboring gene Sharpr-MPRA regulatory region 9563 Neighboring gene NANOG hESC enhancer GRCh37_chr9:112483239-112483742 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_104485 Neighboring gene putative uncharacterized protein DDB_G0287265

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. Joyce CE, et al. Hum Mol Genet, 2011 Oct 15. PMID 21807764, Free PMC Article
  2. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. Creighton CJ, et al. PLoS One, 2010 Mar 10. PMID 20224791, Free PMC Article
  3. Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability. Achuthankutty D, et al. J Cell Biol, 2019 Dec 2. PMID 31615875, Free PMC Article
  4. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Other Names

  • hsa-mir-3927

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037493.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AL162733
    Related
    ENST00000579313.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    109511475..109511545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    121680863..121680933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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