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Nuggc nuclear GTPase, germinal center associated [ Mus musculus (house mouse) ]

Gene ID: 100503545, updated on 23-Jun-2021

Summary

Official Symbol
Nuggcprovided by MGI
Official Full Name
nuclear GTPase, germinal center associatedprovided by MGI
Primary source
MGI:MGI:2685446
See related
Ensembl:ENSMUSG00000061356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SLI; Gm600; SLIP-GC
Expression
Biased expression in testis adult (RPKM 1.5), placenta adult (RPKM 0.4) and 2 other tissues See more
Orthologs
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Genomic context

See Nuggc in Genome Data Viewer
Location:
14; 14 D1
Exon count:
23
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (65830901..65885893)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65593499..65648444)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66220118..66267281)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9530047P18 gene Neighboring gene elongator acetyltransferase complex subunit 3 Neighboring gene predicted gene, 30245 Neighboring gene predicted gene, 53863 Neighboring gene scavenger receptor class A, member 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
nuclear GTPase SLIP-GC
Names
speckled-like pattern in the germinal center

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195674.2NP_001182603.2  nuclear GTPase SLIP-GC

    Status: VALIDATED

    Source sequence(s)
    AC122274
    Consensus CDS
    CCDS56966.1
    UniProtKB/TrEMBL
    D3YY21
    Related
    ENSMUSP00000078434.7, ENSMUST00000079469.7
    Conserved Domains (1) summary
    cl21455
    Location:300466
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    65830901..65885893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518302.2XP_006518365.2  nuclear GTPase SLIP-GC isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:128197
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_036158327.1XP_036014220.1  nuclear GTPase SLIP-GC isoform X3

    Conserved Domains (1) summary
    cl38936
    Location:128197
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_006518301.3XP_006518364.1  nuclear GTPase SLIP-GC isoform X2

    See identical proteins and their annotated locations for XP_006518364.1

    UniProtKB/Swiss-Prot
    D3YWJ0
    Conserved Domains (2) summary
    TIGR03597
    Location:80123
    GTPase_YqeH; ribosome biogenesis GTPase YqeH
    cl38936
    Location:103172
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. XM_006518303.3XP_006518366.1  nuclear GTPase SLIP-GC isoform X2

    See identical proteins and their annotated locations for XP_006518366.1

    UniProtKB/Swiss-Prot
    D3YWJ0
    Related
    ENSMUSP00000118402.2, ENSMUST00000150897.8
    Conserved Domains (2) summary
    TIGR03597
    Location:80123
    GTPase_YqeH; ribosome biogenesis GTPase YqeH
    cl38936
    Location:103172
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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