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Atg14 autophagy related 14 [ Mus musculus (house mouse) ]

Gene ID: 100504663, updated on 25-Nov-2021

Summary

Official Symbol
Atg14provided by MGI
Official Full Name
autophagy related 14provided by MGI
Primary source
MGI:MGI:1261775
See related
Ensembl:ENSMUSG00000037526
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atg14L; 4832427M01; D14Ertd114e; D14Ertd436e
Expression
Ubiquitous expression in placenta adult (RPKM 4.7), CNS E18 (RPKM 4.6) and 28 other tissues See more
Orthologs
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Genomic context

See Atg14 in Genome Data Viewer
Location:
14 C1; 14 24.6 cM
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (47778350..47805891, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (47540893..47568434, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (48130996..48194621, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15 pseudogene Neighboring gene F-box protein 34 Neighboring gene predicted gene, 35166 Neighboring gene small nuclear ribonucleoprotein polypeptide F pseudogene Neighboring gene kinectin 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0831, MGC107607

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTPase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in autophagosome assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in autophagosome maturation ISO
Inferred from Sequence Orthology
more info
 
involved_in autophagosome membrane docking ISO
Inferred from Sequence Orthology
more info
 
involved_in autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular response to glucose starvation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to starvation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to starvation ISO
Inferred from Sequence Orthology
more info
 
involved_in early endosome to late endosome transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within endosome to lysosome transport ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in macroautophagy ISO
Inferred from Sequence Orthology
more info
 
involved_in mitophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitophagy ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of phosphatidylinositol 3-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in posttranscriptional regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of macroautophagy ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of triglyceride metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to mitochondrial depolarisation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in autophagosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in autophagosome ISO
Inferred from Sequence Orthology
more info
 
located_in axoneme IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in extrinsic component of omegasome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extrinsic component of omegasome membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in extrinsic component of phagophore assembly site membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extrinsic component of phagophore assembly site membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondria-associated endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondria-associated endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in phagocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in phagophore assembly site membrane ISO
Inferred from Sequence Orthology
more info
 
part_of phosphatidylinositol 3-kinase complex, class III IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of phosphatidylinositol 3-kinase complex, class III IDA
Inferred from Direct Assay
more info
PubMed 
part_of phosphatidylinositol 3-kinase complex, class III ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
beclin 1-associated autophagy-related key regulator
Names
Atg14-like protein
VATG14 autophagy related 14 homolog
autophagy-related protein 14-like protein
barkor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172599.4NP_766187.1  beclin 1-associated autophagy-related key regulator

    See identical proteins and their annotated locations for NP_766187.1

    Status: VALIDATED

    Source sequence(s)
    AK029967, AK054196, AW123154, BC090995
    Consensus CDS
    CCDS26989.1
    UniProtKB/Swiss-Prot
    Q8CDJ3
    Related
    ENSMUSP00000039047.7, ENSMUST00000042988.7
    Conserved Domains (1) summary
    pfam10186
    Location:43378
    Atg14; Vacuolar sorting 38 and autophagy-related subunit 14

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    47778350..47805891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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