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pigg phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) [ Danio rerio (zebrafish) ]

Gene ID: 100538291, updated on 11-Apr-2024

Summary

Official Symbol
piggprovided by ZNC
Official Full Name
phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)provided by ZNC
Primary source
ZFIN:ZDB-GENE-141215-6
See related
Ensembl:ENSDARG00000038270 AllianceGenome:ZFIN:ZDB-GENE-141215-6
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch73-49o8.1
Summary
Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human PIGG (phosphatidylinositol glycan anchor biosynthesis class G). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (3717768..3944029, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (3610737..3837032, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase pi 1.2 Neighboring gene farnesyltransferase, CAAX box, subunit alpha Neighboring gene LRP2 binding protein Neighboring gene sorting nexin 25 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 6

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables mannose-ethanolamine phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
GPI ethanolamine phosphate transferase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    3717768..3944029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307684.3XP_009305959.1  GPI ethanolamine phosphate transferase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3B8D1
    Conserved Domains (2) summary
    COG1524
    Location:28286
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    cd16024
    Location:66335
    GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G
  2. XM_005173072.4XP_005173129.1  GPI ethanolamine phosphate transferase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BKB6, E7FE54
    Related
    ENSDARP00000055816.5, ENSDART00000055817.7
    Conserved Domains (2) summary
    COG1524
    Location:28286
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    cd16024
    Location:66335
    GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G