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Ugt2b38 UDP glucuronosyltransferase 2 family, polypeptide B38 [ Mus musculus (house mouse) ]

Gene ID: 100559, updated on 8-Feb-2024

Summary

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Official Symbol
Ugt2b38provided by MGI
Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide B38provided by MGI
Primary source
MGI:MGI:2140794
See related
Ensembl:ENSMUSG00000061906 AllianceGenome:MGI:2140794
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9430041C03Rik
Summary
Predicted to enable glucuronosyltransferase activity. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in renal calyx. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human UGT2B15 (UDP glucuronosyltransferase family 2 member B15) and UGT2B17 (UDP glucuronosyltransferase family 2 member B17). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 16.1), liver adult (RPKM 10.6) and 1 other tissue See more
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Genomic context

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Location:
5 E1; 5 43.56 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (87557798..87572062, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (87409939..87424203, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide B36 pseudogene Neighboring gene EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase pseudogene Neighboring gene STARR-seq mESC enhancer starr_13559 Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide A1 Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide A2 Neighboring gene sulfotransferase family 1B, member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glucuronosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucuronosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cellular glucuronidation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in estrogen metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in steroid metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in xenobiotic glucuronidation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear outer membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
UDP glucuronosyltransferase 2 family, polypeptide B38

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133894.2 → NP_598655.1  UDP glucuronosyltransferase 2 family, polypeptide B38 precursor

    See identical proteins and their annotated locations for NP_598655.1

    Status: VALIDATED

    Source sequence(s)
    AC101835
    Consensus CDS
    CCDS19388.1
    UniProtKB/Swiss-Prot
    P17717
    UniProtKB/TrEMBL
    Q91WH2
    Related
    ENSMUSP00000072598.6, ENSMUST00000072818.6
    Conserved Domains (2) summary
    PHA03392
    Location:8 → 506
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:24 → 526
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    87557798..87572062 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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