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RASGEF1A RasGEF domain family member 1A [ Pan troglodytes (chimpanzee) ]

Gene ID: 100615356, updated on 29-Mar-2024

Summary

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Official Symbol
RASGEF1Aprovided by VGNC
Official Full Name
RasGEF domain family member 1Aprovided by VGNC
Primary source
VGNC:VGNC:5713
Locus tag
CK820_G0052378
See related
Ensembl:ENSPTRG00000002444
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (55950150..56022699, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (46623389..46695789, complement)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene ret proto-oncogene Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2 Neighboring gene uncharacterized LOC107976965 Neighboring gene U6atac minor spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-GEF domain-containing family member 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    55950150..56022699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003312542.6 → XP_003312590.1  ras-GEF domain-containing family member 1A isoform X1

    UniProtKB/TrEMBL
    A0A2I3RRK9, A0A2J8IX89, A0A2J8IX97, A0A6D2WZW0
    Related
    ENSPTRP00000067331.1
    Conserved Domains (2) summary
    cd06224
    Location:49 → 176
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:217 → 411
    RasGEF; RasGEF domain

  2. XM_016963085.4 → XP_016818574.1  ras-GEF domain-containing family member 1A isoform X2

    UniProtKB/TrEMBL
    A0A2J8IX97
    Conserved Domains (2) summary
    pfam00617
    Location:138 → 331
    RasGEF; RasGEF domain
    cl02520
    Location:1 → 96
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
Nucleotide Protein
Heading Accession and Version

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