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MANF mesencephalic astrocyte derived neurotrophic factor [ Canis lupus familiaris (dog) ]

Gene ID: 100855747, updated on 8-Mar-2024

Summary

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Official Symbol
MANFprovided by VGNC
Official Full Name
mesencephalic astrocyte derived neurotrophic factorprovided by VGNC
Primary source
VGNC:VGNC:42951
See related
Ensembl:ENSCAFG00845019756
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
ARMET
Orthologs
human mouse all
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Genomic context

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See MANF in Genome Data Viewer
Location:
chromosome: 20
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (38545266..38548938, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (38175958..38179630, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (38602609..38606281, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (37908655..37912327, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (38312971..38316644, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene RAD54 like 2 Neighboring gene uncharacterized LOC102157354 Neighboring gene DDB1 and CUL4 associated factor 1 Neighboring gene uncharacterized LOC119864685 Neighboring gene RNA binding motif protein 15B Neighboring gene dedicator of cytokinesis 3 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in dopaminergic neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor
Names
arginine-rich, mutated in early stage tumors

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    38545266..38548938 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427648.1 → XP_038283576.1  LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor

    UniProtKB/TrEMBL
    A0A8C0YYF9, A0A8I3P5H2
    Related
    ENSCAFP00845027270.1, ENSCAFT00845034817.1
    Conserved Domains (1) summary
    pfam10208
    Location:70 → 214
    Armet; Degradation arginine-rich protein for mis-folding

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    37908655..37912327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503339.1 → XP_038359267.1  LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor

    Conserved Domains (1) summary
    pfam10208
    Location:70 → 214
    Armet; Degradation arginine-rich protein for mis-folding

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    38312971..38316644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630490.1 → XP_038486418.1  LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor

    Conserved Domains (1) summary
    pfam10208
    Location:70 → 214
    Armet; Degradation arginine-rich protein for mis-folding

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    38602609..38606281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566334.1 → XP_038422262.1  LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor

    UniProtKB/TrEMBL
    A0A8C0YYF9, A0A8I3P5H2
    Conserved Domains (1) summary
    pfam10208
    Location:70 → 214
    Armet; Degradation arginine-rich protein for mis-folding

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    38175958..38179630 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003639760.5 → XP_003639808.2  LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor

    UniProtKB/TrEMBL
    A0A8C0YYF9, A0A8I3P5H2
    Conserved Domains (1) summary
    pfam10208
    Location:70 → 214
    Armet; Degradation arginine-rich protein for mis-folding
Nucleotide Protein
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