Defa36 defensin, alpha, 36 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Defa36provided by MGI
Official Full Name: defensin, alpha, 36provided by MGI
Primary source: MGI:MGI:5434853
See related: Ensembl:ENSMUSG00000094662 AllianceGenome:MGI:5434853
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm21498
Summary: Predicted to enable protein homodimerization activity. Predicted to be located in extracellular space. Orthologous to human DEFA1B (defensin alpha 1B); DEFA3 (defensin alpha 3); and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward large intestine adult (RPKM 650.7) See more
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Genomic context

Location:: 8 A2; 8

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (21917444..21918402)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (21427428..21428386)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Defcr17 (e-PCR), detects polymorphism
- UniSTS:186513

NoName (e-PCR)
- UniSTS:490494

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables pore-forming activity	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in midbody	ISO Inferred from Sequence Orthology more info
located_in secretory granule	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: alpha-defensin 5-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.