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VWF von Willebrand factor [ Dasypus novemcinctus (nine-banded armadillo) ]

Gene ID: 100913180, updated on 8-Mar-2024

Summary

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Gene symbol
VWF
Gene description
von Willebrand factor
See related
Ensembl:ENSDNOG00000035788
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Dasypus novemcinctus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Xenarthra; Cingulata; Dasypodidae; Dasypus
Also known as
coi
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
53
Annotation release Status Assembly Chr Location
RS_2023_07 current mDasNov1.hap2 (GCF_030445035.1) 20 NC_080692.1 (24031897..24169017, complement)
102 previous assembly Dasnov3.0 (GCF_000208655.1) Unplaced Scaffold NW_004462314.1 (896210..950741)
102 previous assembly Dasnov3.0 (GCF_000208655.1) Unplaced Scaffold NW_004480308.1 (2461154..2540663, complement)

Chromosome 20 - NC_080692.1Genomic Context describing neighboring genes Neighboring gene neurotrophin 3 Neighboring gene anoctamin 2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC105747169 Neighboring gene CD9 molecule

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The evolution of armadillos, anteaters and sloths depicted by nuclear and mitochondrial phylogenies: implications for the status of the enigmatic fossil Eurotamandua. Delsuc F, et al. Proc Biol Sci, 2001 Aug 7. PMID 11487408, Free PMC Article
  2. Phylogenetic and functional analysis of histidine residues essential for pH-dependent multimerization of von Willebrand factor. Dang LT, et al. J Biol Chem, 2011 Jul 22. PMID 21592973, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-substrate adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
von Willebrand factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001281306.1 → NP_001268235.1  von Willebrand factor precursor

    See identical proteins and their annotated locations for NP_001268235.1

    Status: PROVISIONAL

    Source sequence(s)
    BK007983
    UniProtKB/TrEMBL
    F5XVB2
    Related
    ENSDNOP00000026975.1, ENSDNOT00000039004.1
    Conserved Domains (11) summary
    smart00041
    Location:2726 → 2807
    CT; C-terminal cystine knot-like domain (CTCK)
    smart00214
    Location:2430 → 2493
    VWC; von Willebrand factor (vWF) type C domain
    smart00216
    Location:376 → 539
    VWD; von Willebrand factor (vWF) type D domain
    smart00832
    Location:221 → 291
    C8; This domain contains 8 conserved cysteine residues
    cd01450
    Location:1275 → 1437
    vWFA_subfamily_ECM; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam00092
    Location:1497 → 1657
    VWA; von Willebrand factor type A domain
    pfam00094
    Location:34 → 178
    VWD; von Willebrand factor type D domain
    pfam01826
    Location:651 → 706
    TIL; Trypsin Inhibitor like cysteine rich domain
    pfam08742
    Location:1057 → 1125
    C8; C8 domain
    pfam16164
    Location:1197 → 1275
    VWA_N2; VWA N-terminal
    cl17735
    Location:349 → 393
    VWC; von Willebrand factor type C domain

RefSeqs of Annotated Genomes: GCF_030445035.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mDasNov1.hap2

Genomic

  1. NC_080692.1 Reference mDasNov1.hap2

    Range
    24031897..24169017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_058282316.1 → XP_058138299.1  von Willebrand factor isoform X1

  2. XM_058282317.1 → XP_058138300.1  von Willebrand factor isoform X1

Nucleotide Protein
Heading Accession and Version

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