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Cdh8 cadherin 8 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101709808, updated on 8-Mar-2024

Summary

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Gene symbol
Cdh8
Gene description
cadherin 8
Locus tag
GW7_16623
See related
Ensembl:ENSHGLG00000012608
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Also known as
cadherin-8
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (24348163..24733583)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110348790 Neighboring gene growth hormone-inducible transmembrane protein pseudogene Neighboring gene uncharacterized LOC110348791 Neighboring gene protein PAT1 homolog 1 pseudogene Neighboring gene sentrin-specific protease 3 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression pattern of cadherins in the naked mole rat (Heterocephalus glaber) suggests innate cortical diversification of the cerebrum. Matsunaga E, et al. J Comp Neurol, 2011 Jun 15. PMID 21452207
  2. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adherens junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic cleft IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cadherin-8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    24348163..24733583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004843115.3 → XP_004843172.1  cadherin-8 isoform X1

    See identical proteins and their annotated locations for XP_004843172.1

    UniProtKB/TrEMBL
    G5AL48
    Conserved Domains (3) summary
    cd11304
    Location:171 → 272
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:87 → 165
    CA; Cadherin repeats
    pfam01049
    Location:653 → 790
    Cadherin_C; Cadherin cytoplasmic region

  2. XM_021256953.1 → XP_021112612.1  cadherin-8 isoform X3

    Conserved Domains (3) summary
    cd11304
    Location:171 → 272
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:87 → 165
    CA; Cadherin repeats
    pfam01049
    Location:645 → 697
    Cadherin_C; Cadherin cytoplasmic region

  3. XM_004843118.3 → XP_004843175.1  cadherin-8 isoform X2

    Related
    ENSHGLP00000017620.1, ENSHGLT00000017795.1
    Conserved Domains (3) summary
    cd11304
    Location:171 → 272
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:87 → 165
    CA; Cadherin repeats
    pfam01049
    Location:653 → 702
    Cadherin_C; Cadherin cytoplasmic region

  4. XM_004843117.3 → XP_004843174.1  cadherin-8 isoform X1

    See identical proteins and their annotated locations for XP_004843174.1

    UniProtKB/TrEMBL
    G5AL48
    Conserved Domains (3) summary
    cd11304
    Location:171 → 272
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:87 → 165
    CA; Cadherin repeats
    pfam01049
    Location:653 → 790
    Cadherin_C; Cadherin cytoplasmic region

  5. XM_021256954.1 → XP_021112613.1  cadherin-8 isoform X4

    Conserved Domains (2) summary
    smart00112
    Location:15 → 53
    CA; Cadherin repeats
    pfam01049
    Location:96 → 244
    Cadherin_C; Cadherin cytoplasmic region
Nucleotide Protein
Heading Accession and Version

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