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Tbx5 T-box transcription factor 5 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101720042, updated on 8-Mar-2024

Summary

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Gene symbol
Tbx5
Gene description
T-box transcription factor 5
Locus tag
GW7_10167
See related
Ensembl:ENSHGLG00000016202
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624747.1 (18307294..18348040)

NW_004624747.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101719813 Neighboring gene T-box transcription factor 3 Neighboring gene uncharacterized LOC110348821 Neighboring gene G patch domain and KOW motifs-containing protein pseudogene Neighboring gene thioredoxin domain-containing protein 9-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624747 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cardiac left ventricle formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pattern specification process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
T-box transcription factor TBX5
Names
T-box 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624747.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    18307294..18348040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004843726.1 → XP_004843783.1  T-box transcription factor TBX5

    See identical proteins and their annotated locations for XP_004843783.1

    UniProtKB/TrEMBL
    G5AKX8
    Related
    ENSHGLP00000022716.1, ENSHGLT00000022930.1
    Conserved Domains (1) summary
    cd00182
    Location:53 → 241
    TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
Nucleotide Protein
Heading Accession and Version

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