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MME membrane metalloendopeptidase [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101925772, updated on 8-Mar-2024

Summary

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Gene symbol
MME
Gene description
membrane metalloendopeptidase
See related
Ensembl:ENSMFAG00000039633
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
27
Annotation release Status Assembly Chr Location
102 current MFA1912RKSv2 (GCF_012559485.2) 2 NC_052256.1 (136655465..136760446, complement)
101 previous assembly Macaca_fascicularis_5.0 (GCF_000364345.1) 2 NC_022273.1 (57472188..57576870)

Chromosome 2 - NC_052256.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123571706 Neighboring gene small transmembrane regulator of ion transport 1 Neighboring gene uncharacterized LOC123571872 Neighboring gene uncharacterized LOC107128761

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
  2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neprilysin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca fascicularis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MFA1912RKSv2 Primary Assembly

Genomic

  1. NC_052256.1 Reference MFA1912RKSv2 Primary Assembly

    Range
    136655465..136760446 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005546165.3 → XP_005546222.1  neprilysin

    See identical proteins and their annotated locations for XP_005546222.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Related
    ENSMFAP00000044633.1
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  2. XM_045386746.1 → XP_045242681.1  neprilysin

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  3. XM_005546163.3 → XP_005546220.1  neprilysin

    See identical proteins and their annotated locations for XP_005546220.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  4. XM_005546164.2 → XP_005546221.1  neprilysin

    See identical proteins and their annotated locations for XP_005546221.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  5. XM_005546166.3 → XP_005546223.1  neprilysin

    See identical proteins and their annotated locations for XP_005546223.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  6. XM_045386749.1 → XP_045242684.1  neprilysin

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  7. XM_015445220.2 → XP_015300706.1  neprilysin

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  8. XM_005546162.2 → XP_005546219.1  neprilysin

    See identical proteins and their annotated locations for XP_005546219.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  9. XM_005546161.3 → XP_005546218.1  neprilysin

    See identical proteins and their annotated locations for XP_005546218.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  10. XM_045386750.1 → XP_045242685.1  neprilysin

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  11. XM_005546159.2 → XP_005546216.1  neprilysin

    See identical proteins and their annotated locations for XP_005546216.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  12. XM_045386748.1 → XP_045242683.1  neprilysin

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  13. XM_005546160.2 → XP_005546217.1  neprilysin

    See identical proteins and their annotated locations for XP_005546217.1

    UniProtKB/TrEMBL
    A0A2K5X580, A0A8J8YT08, G7NZK8
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
Nucleotide Protein
Heading Accession and Version

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