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MFN2 mitofusin 2 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101926564, updated on 7-Jun-2024

Summary

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Gene symbol
MFN2
Gene description
mitofusin 2
See related
Ensembl:ENSMFAG00000045034
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MFN2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 1 NC_088375.1 (222787664..222819385, complement)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 1 NC_052255.1 (210797710..210829457, complement)

Chromosome 1 - NC_088375.1Genomic Context describing neighboring genes Neighboring gene migration and invasion inhibitory protein Neighboring gene inositol monophosphatase 1-like Neighboring gene procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Neighboring gene KIAA2013 ortholog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
  2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial fusion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrion localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitofusin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088375.1 Reference T2T-MFA8v1.0

    Range
    222787664..222819385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005544769.4 → XP_005544826.1  mitofusin-2 isoform X1

    See identical proteins and their annotated locations for XP_005544826.1

    UniProtKB/TrEMBL
    A0A2K5VRB6, A0A2K5VRH2, A0A8J8YMS9, Q4R5A0
    Related
    ENSMFAP00000027362.1
    Conserved Domains (2) summary
    cd09912
    Location:97 → 349
    DLP_2; Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins
    pfam04799
    Location:596 → 754
    Fzo_mitofusin; fzo-like conserved region

  2. XM_015451870.3 → XP_015307356.1  mitofusin-2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5VRB6, A0A2K5VRH2, A0A8J8YMS9, Q4R5A0
    Conserved Domains (2) summary
    cd09912
    Location:97 → 349
    DLP_2; Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins
    pfam04799
    Location:596 → 754
    Fzo_mitofusin; fzo-like conserved region

  3. XM_045380564.2 → XP_045236499.1  mitofusin-2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5VRB6, A0A2K5VRH2, A0A8J8YMS9, Q4R5A0
    Conserved Domains (2) summary
    cd09912
    Location:97 → 349
    DLP_2; Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins
    pfam04799
    Location:596 → 754
    Fzo_mitofusin; fzo-like conserved region

  4. XM_015451874.3 → XP_015307360.1  mitofusin-2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5VRB6, A0A2K5VRH2, A0A8J8YMS9, Q4R5A0
    Conserved Domains (2) summary
    cd09912
    Location:97 → 349
    DLP_2; Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins
    pfam04799
    Location:596 → 754
    Fzo_mitofusin; fzo-like conserved region

  5. XM_045380598.2 → XP_045236533.1  mitofusin-2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5VRB6, A0A2K5VRH2, A0A8J8YMS9, Q4R5A0
    Conserved Domains (2) summary
    cd09912
    Location:97 → 349
    DLP_2; Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins
    pfam04799
    Location:596 → 754
    Fzo_mitofusin; fzo-like conserved region

  6. XM_005544766.4 → XP_005544823.1  mitofusin-2 isoform X1

    See identical proteins and their annotated locations for XP_005544823.1

    UniProtKB/TrEMBL
    A0A2K5VRB6, A0A2K5VRH2, A0A8J8YMS9, Q4R5A0
    Related
    ENSMFAP00000027344.1
    Conserved Domains (2) summary
    cd09912
    Location:97 → 349
    DLP_2; Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins
    pfam04799
    Location:596 → 754
    Fzo_mitofusin; fzo-like conserved region

  7. XM_065529781.1 → XP_065385853.1  mitofusin-2 isoform X1

  8. XM_045380592.2 → XP_045236527.1  mitofusin-2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5VRB6, A0A2K5VRH2, A0A8J8YMS9, Q4R5A0
    Conserved Domains (2) summary
    cd09912
    Location:97 → 349
    DLP_2; Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins
    pfam04799
    Location:596 → 754
    Fzo_mitofusin; fzo-like conserved region

  9. XM_065529790.1 → XP_065385862.1  mitofusin-2 isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001284676.1: Suppressed sequence

    Description
    NM_001284676.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version

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