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Smim19 small integral membrane protein 19 [ Mus musculus (house mouse) ]

Gene ID: 102032, updated on 5-Mar-2024

Summary

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Official Symbol
Smim19provided by MGI
Official Full Name
small integral membrane protein 19provided by MGI
Primary source
MGI:MGI:2142501
See related
Ensembl:ENSMUSG00000031534 AllianceGenome:MGI:2142501
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EST-c39
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in germ cell of testis. Orthologous to human SMIM19 (small integral membrane protein 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 12.0), cerebellum adult (RPKM 11.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 A2; 8 11.42 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22952630..22966850, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (22462614..22476879, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_20903 Neighboring gene mitochondrial ribosomal protein S31 Neighboring gene STARR-seq mESC enhancer starr_20904 Neighboring gene predicted gene, 39140 Neighboring gene STARR-positive B cell enhancer ABC_E9722 Neighboring gene solute carrier family 20, member 2 Neighboring gene STARR-seq mESC enhancer starr_20908 Neighboring gene voltage-dependent anion channel 3 Neighboring gene predicted gene, 30086

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Spermatogonia-dependent expression of testicular genes in mice. Tanaka K, et al. Dev Biol, 2002 Jun 15. PMID 12051830
  2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
small integral membrane protein 19
Names
UPF0697 protein C8orf40 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012667.3 → NP_001012685.2  small integral membrane protein 19 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC140326
    Consensus CDS
    CCDS52521.1
    UniProtKB/TrEMBL
    E9PUT6
    Related
    ENSMUSP00000131855.2, ENSMUST00000163774.3
    Conserved Domains (1) summary
    pfam15117
    Location:15 → 112
    UPF0697; uncharacterized protein family UPF0697

  2. NM_001146117.2 → NP_001139589.1  small integral membrane protein 19 isoform 2

    See identical proteins and their annotated locations for NP_001139589.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AC140326
    Consensus CDS
    CCDS52520.1
    UniProtKB/Swiss-Prot
    Q80ZU4
    Related
    ENSMUSP00000033935.9, ENSMUST00000033935.16
    Conserved Domains (1) summary
    pfam15117
    Location:10 → 107
    UPF0697; Uncharacterized protein family UPF0697

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    22952630..22966850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80ZU4.2 GenPept UniProtKB/Swiss-Prot:Q80ZU4

Gene LinkOut

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