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ESR1 estrogen receptor 1 [ Alligator sinensis (Chinese alligator) ]

Gene ID: 102376369, updated on 10-Mar-2024

Summary

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Gene symbol
ESR1
Gene description
estrogen receptor 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005842120.1 (1378970..1680817, complement)

NW_005842120.1Genomic Context describing neighboring genes Neighboring gene MYC target 1 Neighboring gene spectrin repeat containing nuclear envelope protein 1 Neighboring gene uncharacterized LOC102376204 Neighboring gene coiled-coil domain containing 170 Neighboring gene acidic residue methyltransferase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005842120 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning, characterization, tissue distribution and mRNA expression changes during the hibernation and reproductive periods of estrogen receptor alpha (ESR1) in Chinese alligator, Alligator sinensis. Zhang R, et al. Comp Biochem Physiol B Biochem Mol Biol, 2016 Oct. PMID 27212643

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ESR1 mRNA level in the brain of crocodilians, and the distribution
    Title: Molecular cloning, characterization, tissue distribution and mRNA expression changes during the hibernation and reproductive periods of estrogen receptor alpha (ESR1) in Chinese alligator, Alligator sinensis.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear estrogen receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in steroid hormone mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
estrogen receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM45574v1 Primary Assembly

Genomic

  1. NW_005842120.1 Reference ASM45574v1 Primary Assembly

    Range
    1378970..1680817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014520478.2 → XP_014375964.2  estrogen receptor isoform X3

    UniProtKB/TrEMBL
    A0A1U8DE24, A0A2H4EW99

  2. XM_025205609.1 → XP_025061394.1  estrogen receptor isoform X1

    UniProtKB/TrEMBL
    A0A2H4EW99, A0A3Q0GNM7

  3. XM_025205612.1 → XP_025061397.1  estrogen receptor isoform X4

    UniProtKB/TrEMBL
    A0A1U7RVZ7, A0A2H4EW99
    Conserved Domains (4) summary
    cd06949
    Location:304 → 541
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:174 → 255
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:42 → 175
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:551 → 587
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal

  4. XM_025205611.1 → XP_025061396.1  estrogen receptor isoform X4

    UniProtKB/TrEMBL
    A0A1U7RVZ7, A0A2H4EW99
    Conserved Domains (4) summary
    cd06949
    Location:304 → 541
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:174 → 255
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:42 → 175
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:551 → 587
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal

  5. XM_006024833.3 → XP_006024895.1  estrogen receptor isoform X4

    UniProtKB/TrEMBL
    A0A1U7RVZ7, A0A2H4EW99
    Conserved Domains (4) summary
    cd06949
    Location:304 → 541
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:174 → 255
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:42 → 175
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:551 → 587
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal

  6. XM_025205610.1 → XP_025061395.1  estrogen receptor isoform X2

    UniProtKB/TrEMBL
    A0A2H4EW99, A0A3Q0GT86
Nucleotide Protein
Heading Accession and Version

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