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TLR5 toll like receptor 5 [ Tupaia chinensis (Chinese tree shrew) ]

Gene ID: 102478354, updated on 10-Mar-2024

Summary

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Gene symbol
TLR5
Gene description
toll like receptor 5
Locus tag
TREES_T100015517
Gene type
protein coding
RefSeq status
MODEL
Organism
Tupaia chinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
102 current TupChi_1.0 (GCF_000334495.1) Unplaced Scaffold NW_006210013.1 (271914..302935, complement)

NW_006210013.1Genomic Context describing neighboring genes Neighboring gene dispatched RND transporter family member 1 Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 pseudogene Neighboring gene 40S ribosomal protein S6 pseudogene Neighboring gene sushi domain-containing protein 4 Neighboring gene sushi domain containing 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006210013 Unplaced Scaffold Reference TupChi_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of toll-like receptors (TLRs) in the Chinese tree shrew (Tupaia belangeri chinensis). Yu D, et al. Dev Comp Immunol, 2016 Jul. PMID 26923770
  2. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. Yan H, et al. Elife, 2012 Nov 13. PMID 23150796, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tupaia chinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TupChi_1.0

Genomic

  1. NW_006210013.1 Reference TupChi_1.0

    Range
    271914..302935 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006171978.3 → XP_006172040.1  toll-like receptor 5 isoform X4

    UniProtKB/TrEMBL
    A0A140H1B9
    Conserved Domains (5) summary
    smart00082
    Location:595 → 646
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:458 → 576
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:211 → 223
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:305 → 326
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:306 → 361
    LRR_8; Leucine rich repeat

  2. XM_014585642.2 → XP_014441128.1  toll-like receptor 5 isoform X3

    UniProtKB/TrEMBL
    A0A140H1B9
    Conserved Domains (5) summary
    smart00082
    Location:595 → 646
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:458 → 576
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:211 → 223
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:305 → 326
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:306 → 361
    LRR_8; Leucine rich repeat

  3. XM_006171976.3 → XP_006172038.1  toll-like receptor 5 isoform X2

    See identical proteins and their annotated locations for XP_006172038.1

    UniProtKB/TrEMBL
    A0A140H1B9
    Conserved Domains (6) summary
    smart00082
    Location:582 → 633
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:445 → 563
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:198 → 210
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:292 → 313
    LRR_RI; leucine-rich repeat [structural motif]
    pfam01582
    Location:696 → 846
    TIR; TIR domain
    pfam13855
    Location:293 → 348
    LRR_8; Leucine rich repeat

  4. XM_006171975.3 → XP_006172037.1  toll-like receptor 5 isoform X1

    UniProtKB/TrEMBL
    A0A140H1B9
    Conserved Domains (6) summary
    smart00082
    Location:595 → 646
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:458 → 576
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:211 → 223
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:305 → 326
    LRR_RI; leucine-rich repeat [structural motif]
    pfam01582
    Location:709 → 859
    TIR; TIR domain
    pfam13855
    Location:306 → 361
    LRR_8; Leucine rich repeat
Nucleotide Protein
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