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TLR1 toll like receptor 1 [ Tupaia chinensis (Chinese tree shrew) ]

Gene ID: 102493675, updated on 10-Mar-2024

Summary

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Gene symbol
TLR1
Gene description
toll like receptor 1
Locus tag
TREES_T100003652
Gene type
protein coding
RefSeq status
MODEL
Organism
Tupaia chinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia
Orthologs
human mouse all
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Genomic context

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See TLR1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
2
Annotation release Status Assembly Chr Location
102 current TupChi_1.0 (GCF_000334495.1) Unplaced Scaffold NW_006206760.1 (2387654..2396230)

NW_006206760.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 114 member A1 Neighboring gene toll like receptor 6 Neighboring gene KLF transcription factor 3 Neighboring gene uncharacterized LOC102494794

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006206760 Unplaced Scaffold Reference TupChi_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of toll-like receptors (TLRs) in the Chinese tree shrew (Tupaia belangeri chinensis). Yu D, et al. Dev Comp Immunol, 2016 Jul. PMID 26923770

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Toll-like receptor 2 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipopeptide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to triacyl bacterial lipopeptide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Toll-like receptor 1-Toll-like receptor 2 protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tupaia chinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TupChi_1.0

Genomic

  1. NW_006206760.1 Reference TupChi_1.0

    Range
    2387654..2396230
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006169244.3 → XP_006169306.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A140H1B5
    Conserved Domains (6) summary
    smart00082
    Location:524 → 577
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:636 → 779
    TIR; Toll - interleukin 1 - resistance
    cd00116
    Location:49 → 151
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:47 → 70
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:352 → 373
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:48 → 105
    LRR_8; Leucine rich repeat
Nucleotide Protein
Heading Accession and Version

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