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MMP12 matrix metallopeptidase 12 [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102520612, updated on 10-Mar-2024

Summary

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Gene symbol
MMP12
Gene description
matrix metallopeptidase 12
Locus tag
CB1_000877047
See related
EnsemblRapid:ENSCFEG00005001167
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
10
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 10 NC_045705.1 (3063839..3073581)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006211052.1 (4914191..4923464)

Chromosome 10 - NC_045705.1Genomic Context describing neighboring genes Neighboring gene defective in cullin neddylation 1 domain containing 5 Neighboring gene matrix metallopeptidase 13 Neighboring gene transfer RNA alanine (anticodon GGC) Neighboring gene matrix metallopeptidase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequences of wild and domestic bactrian camels. Bactrian Camels Genome Sequencing and Analysis Consortium, et al. Nat Commun, 2012. PMID 23149746, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
macrophage metalloelastase
Names
matrix metallopeptidase 12 (macrophage elastase)
matrix metallopeptidase 12-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045705.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    3063839..3073581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006186218.3 → XP_006186280.1  macrophage metalloelastase

    UniProtKB/TrEMBL
    A0A8B6YGT6
    Related
    ENSCFEP00005001632.1, ENSCFET00005001907.1
    Conserved Domains (3) summary
    cd00094
    Location:282 → 468
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:110 → 264
    Peptidase_M10; Matrixin
    pfam01471
    Location:27 → 88
    PG_binding_1; Putative peptidoglycan binding domain
Nucleotide Protein
Heading Accession and Version

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