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WWOX-AS1 WWOX antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 102724047, updated on 10-Oct-2023

Summary

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Official Symbol
WWOX-AS1provided by HGNC
Official Full Name
WWOX antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:53169
See related
Ensembl:ENSG00000260969 AllianceGenome:HGNC:53169
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward testis (RPKM 5.3) See more
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Genomic context

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See WWOX-AS1 in Genome Data Viewer
Location:
16q23.1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (78234662..78241751, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (84290863..84297955, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984897 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_45663 Neighboring gene leucine rich repeat containing 59 pseudogene Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_45737 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_45804 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_45838 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:78133785-78134284 Neighboring gene keratin 8 pseudogene 22 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_45974 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_45980 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_46047 Neighboring gene Sharpr-MPRA regulatory region 1447 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:78247857-78248356 Neighboring gene WW domain containing oxidoreductase Neighboring gene Sharpr-MPRA regulatory region 10407 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_46108 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:78337176-78337676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:78337677-78338177 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:78345064-78345644 Neighboring gene NANOG hESC enhancer GRCh37_chr16:78347375-78347876 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_46172 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_46191 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_46196 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:78405950-78406582 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:78455072-78455805 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_46257 Neighboring gene Sharpr-MPRA regulatory region 4302 Neighboring gene LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 5 Neighboring gene uncharacterized LOC124903728

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LncRNA WWOX‑AS1 inhibits the proliferation, migration and invasion of osteosarcoma cells. Qu G, et al. Mol Med Rep, 2018 Jul. PMID 29845204, Free PMC Article
  2. A new tumor suppressor lncRNA RP11-190D6.2 inhibits the proliferation, migration, and invasion of epithelial ovarian cancer cells. Tong W, et al. Onco Targets Ther, 2017. PMID 28280357, Free PMC Article
  3. LncRNA WWOX-AS1 sponges miR-20b-5p in hepatocellular carcinoma and represses its progression by upregulating WWOX. Xu D, et al. Cancer Biol Ther, 2020 Oct 2. PMID 32931356, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • RP11-190D6.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_184271.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC009044
    Related
    ENST00000666211.1

  2. NR_184272.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC009044
    Related
    ENST00000664344.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    78234662..78241751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    84290863..84297955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases