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GM2A GM2 ganglioside activator [ Chelonia mydas (Green sea turtle) ]

Gene ID: 102946441, updated on 10-Mar-2024

Summary

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Gene symbol
GM2A
Gene description
GM2 ganglioside activator
See related
EnsemblRapid:ENSCMYG00015018450
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonia mydas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
5
Annotation release Status Assembly Chr Location
103 current rCheMyd1.pri.v2 (GCF_015237465.2) 8 NC_057854.1 (6315395..6330395, complement)
102 previous assembly rCheMyd1.pri (GCF_015237465.1) 8 NC_051248.1 (6316983..6332635, complement)

Chromosome 8 - NC_057854.1Genomic Context describing neighboring genes Neighboring gene melatonin receptor type 1A Neighboring gene proton-coupled amino acid transporter 1 Neighboring gene coiled-coil domain containing 69 Neighboring gene platelet-derived growth factor receptor-like protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. Duffy DJ, et al. Commun Biol, 2018. PMID 30271945, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables enzyme activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipid transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ganglioside catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ganglioside GM2 activator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rCheMyd1.pri.v2 Primary Assembly

Genomic

  1. NC_057854.1 Reference rCheMyd1.pri.v2 Primary Assembly

    Range
    6315395..6330395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037907862.2 → XP_037763790.1  ganglioside GM2 activator isoform X2

    Related
    ENSCMYP00015028536.1, ENSCMYT00015034749.1
    Conserved Domains (1) summary
    cl00274
    Location:19 → 179
    ML; The ML (MD-2-related lipid-recognition) domain is present in MD-1, MD-2, GM2 activator protein, Niemann-Pick type C2 (Npc2) protein, phosphatidylinositol/phosphatidylglycerol transfer protein (PG/PI-TP), mite allergen Der p 2 and several proteins of ...

  2. XM_037907860.2 → XP_037763788.1  ganglioside GM2 activator isoform X1

    Related
    ENSCMYP00015028521.1, ENSCMYT00015034734.1
    Conserved Domains (1) summary
    cl00274
    Location:41 → 201
    ML; The ML (MD-2-related lipid-recognition) domain is present in MD-1, MD-2, GM2 activator protein, Niemann-Pick type C2 (Npc2) protein, phosphatidylinositol/phosphatidylglycerol transfer protein (PG/PI-TP), mite allergen Der p 2 and several proteins of ...
Nucleotide Protein
Heading Accession and Version

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