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putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [ Escherichia coli CFT073 ]

Gene ID: 1040013, discontinued on 20-May-2015
  • This record was discontinued.

Summary

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Gene symbol
putA
Gene description
trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase
Locus tag
c1151
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli CFT073 (strain: CFT073)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
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Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004431.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structural basis of DNA recognition by PutA and three-dimensional structural details of the PutA dimer interface.
    Title: Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition.
  2. Switching of PutA from a transcriptional repressor to a membrane-bound protein involves W211 amino acid in a flexible domain near the active site and occurs on a time scale that is >10-fold slower than the turnover number of PutA.
    Title: Exploring the proline-dependent conformational change in the multifunctional PutA flavoprotein by tryptophan fluorescence spectroscopy.
Submit: New GeneRIF Correction

General protein information

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Names
trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase
NP_753076.3
  • proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004431.1 Reference assembly

    Range
    1108415..1112443 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_753076.3 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [Escherichia coli CFT073]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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