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Aspg asparaginase [ Mus musculus (house mouse) ]

Gene ID: 104816, updated on 6-May-2021

Summary

Official Symbol
Aspgprovided by MGI
Official Full Name
asparaginaseprovided by MGI
Primary source
MGI:MGI:2144822
See related
Ensembl:ENSMUSG00000037686
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm690; AI429460; A530050D06Rik
Expression
Biased expression in liver adult (RPKM 84.5), colon adult (RPKM 14.5) and 7 other tissues See more
Orthologs
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Genomic context

See Aspg in Genome Data Viewer
Location:
12; 12 F1
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (112073117..112094007)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (112106683..112127573)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (113344894..113365784)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene tudor domain containing 9 Neighboring gene retinal degeneration 3-like Neighboring gene predicted gene, 46381 Neighboring gene microRNA 3073a Neighboring gene microRNA 3073b Neighboring gene microRNA 203b Neighboring gene microRNA 203 Neighboring gene kinesin family member 26A

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 1-alkyl-2-acetylglycerophosphocholine esterase activity ISO
Inferred from Sequence Orthology
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity, transferring groups other than amino-acyl groups ISO
Inferred from Sequence Orthology
more info
 
enables asparaginase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables asparaginase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables lysophospholipase activity ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidyl phospholipase B activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within asparagine metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phospholipid metabolic process ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
60 kDa lysophospholipase
Names
60 kDa lysophospholipase [Includes: L-asparaginase
asparaginase homolog
lysophospholipase-transacylase
NP_001074638.1
XP_006515408.1
XP_006515409.1
XP_006515410.1
XP_006515411.1
XP_006515412.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081169.1NP_001074638.1  60 kDa lysophospholipase

    See identical proteins and their annotated locations for NP_001074638.1

    Status: PROVISIONAL

    Source sequence(s)
    AC112520
    Consensus CDS
    CCDS36567.1
    UniProtKB/Swiss-Prot
    A0JNU3
    Related
    ENSMUSP00000078369.5, ENSMUST00000079400.6
    Conserved Domains (3) summary
    PLN03192
    Location:373550
    PLN03192; Voltage-dependent potassium channel; Provisional
    sd00045
    Location:430461
    ANK; ANK repeat [structural motif]
    cl00216
    Location:9361
    L-asparaginase_like; Bacterial L-asparaginases and related enzymes

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    112073117..112094007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515345.5XP_006515408.1  60 kDa lysophospholipase isoform X1

    Conserved Domains (3) summary
    PLN03192
    Location:330507
    PLN03192; Voltage-dependent potassium channel; Provisional
    sd00045
    Location:387418
    ANK; ANK repeat [structural motif]
    cl00216
    Location:31318
    L-asparaginase_like; Bacterial L-asparaginases and related enzymes
  2. XM_006515346.1XP_006515409.1  60 kDa lysophospholipase isoform X2

    See identical proteins and their annotated locations for XP_006515409.1

    Conserved Domains (3) summary
    PLN03192
    Location:255432
    PLN03192; Voltage-dependent potassium channel; Provisional
    sd00045
    Location:312343
    ANK; ANK repeat [structural motif]
    cl00216
    Location:1243
    L-asparaginase_like; Bacterial L-asparaginases and related enzymes
  3. XM_006515349.1XP_006515412.1  60 kDa lysophospholipase isoform X3

    Conserved Domains (3) summary
    PLN03192
    Location:211388
    PLN03192; Voltage-dependent potassium channel; Provisional
    sd00045
    Location:268299
    ANK; ANK repeat [structural motif]
    cl00216
    Location:2199
    L-asparaginase_like; Bacterial L-asparaginases and related enzymes
  4. XM_006515348.1XP_006515411.1  60 kDa lysophospholipase isoform X2

    See identical proteins and their annotated locations for XP_006515411.1

    Conserved Domains (3) summary
    PLN03192
    Location:255432
    PLN03192; Voltage-dependent potassium channel; Provisional
    sd00045
    Location:312343
    ANK; ANK repeat [structural motif]
    cl00216
    Location:1243
    L-asparaginase_like; Bacterial L-asparaginases and related enzymes
  5. XM_006515347.5XP_006515410.1  60 kDa lysophospholipase isoform X2

    See identical proteins and their annotated locations for XP_006515410.1

    Conserved Domains (3) summary
    PLN03192
    Location:255432
    PLN03192; Voltage-dependent potassium channel; Provisional
    sd00045
    Location:312343
    ANK; ANK repeat [structural motif]
    cl00216
    Location:1243
    L-asparaginase_like; Bacterial L-asparaginases and related enzymes
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