U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gm6749 predicted pseudogene 6749 [ Mus musculus (house mouse) ]

Gene ID: 105242736, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Gm6749provided by MGI
Official Full Name
predicted pseudogene 6749provided by MGI
Primary source
MGI:MGI:3648518
See related
AllianceGenome:MGI:3648518
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm44122; EG627371
Expression
Ubiquitous expression in CNS E14 (RPKM 86.3), CNS E11.5 (RPKM 82.6) and 28 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
6 E2; 6 49.87 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (108857755..108859599)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (108880794..108882707)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 8B Neighboring gene predicted gene, 51409 Neighboring gene predicted gene, 35417 Neighboring gene STARR-positive B cell enhancer mm9_chr6:108775076-108775377 Neighboring gene STARR-positive B cell enhancer ABC_E3668 Neighboring gene STARR-positive B cell enhancer ABC_E3669 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:108785919-108786120 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:108786185-108786368 Neighboring gene ER degradation enhancer, mannosidase alpha-like 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:108789575-108789776 Neighboring gene predicted gene, 53302 Neighboring gene cardiac injury-related Bclaf1-inhibiting lncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Harada A, et al. Nat Commun, 2018 Apr 11. PMID 29643389, Free PMC Article
  2. Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells. Wang Y, et al. BMC Biol, 2018 Sep 24. PMID 30249243, Free PMC Article
  3. Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization. Park J, et al. Nucleic Acids Res, 2018 Dec 14. PMID 30335163, Free PMC Article
  4. UBN1/2 of HIRA complex is responsible for recognition and deposition of H3.3 at cis-regulatory elements of genes in mouse ES cells. Xiong C, et al. BMC Biol, 2018 Oct 3. PMID 30285846, Free PMC Article
  5. PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX. Delbarre E, et al. Genome Res, 2017 Jun. PMID 28341773, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A lncRNA ChRO1 specifically associates with ATRX/DAXX/H3.3 complex at chromocenters to promote H3.3 incorporation and transcriptional induction of satellite repeats, which is essential for chromocenter clustering thus unveiling a mechanism involving a lncRNA that plays a role in large-scale heterochromatin reorganization and cell differentiation.
    Title: Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization.
  2. This study provides key insights into the mechanism of how histone variants H3.3 and H2A.Z function coordinately to finely tune the PRC2 enzymatic activity during gene silencing, through promoting or impairing chromosome compaction respectively.
    Title: Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells.
  3. This study demonstrates that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3.3 by the HIRA complex.
    Title: UBN1/2 of HIRA complex is responsible for recognition and deposition of H3.3 at cis-regulatory elements of genes in mouse ES cells.
  4. Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
    Title: Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
  5. PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX and DAXX.
    Title: PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

General protein information

Go to the top of the page Help
Preferred Names
histone H3.3A-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    108857755..108859599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017321875.3 → XP_017177364.1  histone H3.3A-like

    UniProtKB/TrEMBL
    A1L0U3
    Conserved Domains (1) summary
    PTZ00018
    Location:8 → 140
    PTZ00018; histone H3; Provisional
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.