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Utp15 UTP15 small subunit processome component [ Mus musculus (house mouse) ]

Gene ID: 105372, updated on 11-Apr-2024

Summary

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Official Symbol
Utp15provided by MGI
Official Full Name
UTP15 small subunit processome componentprovided by MGI
Primary source
MGI:MGI:2145443
See related
Ensembl:ENSMUSG00000041747 AllianceGenome:MGI:2145443
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in positive regulation of rRNA processing; positive regulation of transcription by RNA polymerase I; and rRNA processing. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in endoplasmic reticulum and fibrillar center. Predicted to be active in nucleolus. Orthologous to human UTP15 (UTP15 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 7.4), placenta adult (RPKM 5.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Utp15 in Genome Data Viewer
Location:
13 D1; 13 51.87 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (98383353..98399500, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (98246845..98262992, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 28 Neighboring gene predicted gene, 57601 Neighboring gene STARR-seq mESC enhancer starr_35412 Neighboring gene predicted gene, 34469 Neighboring gene STARR-seq mESC enhancer starr_35415 Neighboring gene STARR-positive B cell enhancer ABC_E5411 Neighboring gene ankyrin repeat family A member 2 Neighboring gene STARR-seq mESC enhancer starr_35417 Neighboring gene predicted gene 21976

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article
  2. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Rudra D, et al. Nat Immunol, 2012 Oct. PMID 22922362, Free PMC Article
  3. Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins. Lang B, et al. Nucleic Acids Res, 2021 Jul 9. PMID 34133714, Free PMC Article
  4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in positive regulation of rRNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase I ISO
Inferred from Sequence Orthology
more info
  
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
U3 small nucleolar RNA-associated protein 15 homolog
Names
UTP15, U3 small nucleolar ribonucleoprotein, homolog
src-associated protein SAW

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178918.3 → NP_849249.1  U3 small nucleolar RNA-associated protein 15 homolog

    See identical proteins and their annotated locations for NP_849249.1

    Status: PROVISIONAL

    Source sequence(s)
    AC123056
    Consensus CDS
    CCDS26712.1
    UniProtKB/Swiss-Prot
    Q3TRG8, Q8C7V3, Q8K231
    UniProtKB/TrEMBL
    Q3TN42
    Related
    ENSMUSP00000048204.3, ENSMUST00000040972.4
    Conserved Domains (4) summary
    COG2319
    Location:28 → 310
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:39 → 298
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam09384
    Location:343 → 487
    UTP15_C; UTP15 C terminal
    sd00039
    Location:41 → 78
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    98383353..98399500 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C7V3.1 GenPept UniProtKB/Swiss-Prot:Q8C7V3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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