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ZMYND11 zinc finger MYND-type containing 11 [ Homo sapiens (human) ]

Gene ID: 10771, updated on 3-Apr-2024

Summary

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Official Symbol
ZMYND11provided by HGNC
Official Full Name
zinc finger MYND-type containing 11provided by HGNC
Primary source
HGNC:HGNC:16966
See related
Ensembl:ENSG00000015171 MIM:608668; AllianceGenome:HGNC:16966
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BS69; BRAM1; MRD30
Summary
The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in thyroid (RPKM 38.3), brain (RPKM 25.5) and 25 other tissues See more
Orthologs
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Genomic context

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Location:
10p15.3
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (130088..254637)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (122992..247610)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (176028..300577)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr10:93160-93307 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2890 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2057 Neighboring gene tubulin beta 8 class VIII Neighboring gene IL9R pseudogene 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:180644-180822 Neighboring gene Sharpr-MPRA regulatory region 15592 Neighboring gene RNA, 5S ribosomal pseudogene 297 Neighboring gene DEAD-box helicase 20 pseudogene 1 Neighboring gene uncharacterized LOC107984190 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:294268-295467 Neighboring gene uncharacterized LOC107984191 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:310208-311407 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:315279-315788 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:315789-316297 Neighboring gene RNA, 5S ribosomal pseudogene 298 Neighboring gene disco interacting protein 2 homolog C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder. Oates S, et al. Clin Genet, 2021 Oct. PMID 34216016
  2. ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum. Yates TM, et al. Hum Mutat, 2020 May. PMID 32097528
  3. The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species. Zhang A, et al. Viruses, 2018 Nov 22. PMID 30469473, Free PMC Article
  4. Phenotype comparison confirms ZMYND11 as a critical gene for 10p15.3 microdeletion syndrome. Tumiene B, et al. J Appl Genet, 2017 Nov. PMID 28933030
  5. A de novo missense mutation in ZMYND11 is associated with global developmental delay, seizures, and hypotonia. Moskowitz AM, et al. Cold Spring Harb Mol Case Stud, 2016 Sep. PMID 27626064, Free PMC Article

See all (67) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MicroRNA-196b promotes cell growth and metastasis of ovarian cancer by targeting ZMYND11.
    Title: MicroRNA-196b promotes cell growth and metastasis of ovarian cancer by targeting ZMYND11.
  2. Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.
    Title: Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.
  3. ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder.
    Title: ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder.
  4. ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.
    Title: ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.
  5. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.
    Title: ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.
  6. Our data indicate that increased association with BS69 restricts the function of type 2 EBNA2 as a transcriptional activator and driver of B cell growth and may contribute to reduced B-cell transformation by type 2 EBV.
    Title: Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity.
  7. the E1A proteins from HAdV-C5 and -A12 bind the cellular repressor protein BS69. This occurs via a SLiM containing a conserved PXLXP motif, which is present in CR2 of E1A. This SLiM confers interaction with the MYND domain of BS69.
    Title: The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species.
  8. The ZMYND11 gene has important functions in epigenetic regulation.
    Title: Phenotype comparison confirms ZMYND11 as a critical gene for 10p15.3 microdeletion syndrome.
  9. Taken together, ZMYND11 was demonstrated to be a potential and extremely promising suppressor of GBM, while miRNA-196a-5p was quite an important target of treatment of GBM.
    Title: Downregulation of ZMYND11 induced by miR-196a-5p promotes the progression and growth of GBM.
  10. Interaction with ZMYND11 mediates opposing roles of Ras-responsive ETS1 and ETS2.
    Title: Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.
Submit: New GeneRIF Correction See all GeneRIFs (26)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Intellectual disability, autosomal dominant 30
MedGen: C4015167 OMIM: 616083 GeneReviews: Not available
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Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated 2018-03-28)

ClinGen Genome Curation PagePubMed
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated 2018-03-28)

ClinGen Genome Curation PagePubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC111056

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables methylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylated histone binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables methylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription corepressor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response to virus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of JNK cascade IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of canonical NF-kappaB signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription elongation by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
zinc finger MYND domain-containing protein 11
Names
adenovirus 5 E1A-binding protein
bone morphogenetic protein receptor-associated molecule 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029960.1 RefSeqGene

    Range
    5991..125173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202464.3 → NP_001189393.1  zinc finger MYND domain-containing protein 11 isoform c

    See identical proteins and their annotated locations for NP_001189393.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4), as well as variants 16-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000385484.1, ENST00000403354.5
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  2. NM_001202465.3 → NP_001189394.1  zinc finger MYND domain-containing protein 11 isoform d

    See identical proteins and their annotated locations for NP_001189394.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variant 23, encodes isoform d.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS55697.1
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:187 → 268
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:478 → 513
    zf-MYND; MYND finger
    cl02556
    Location:95 → 173
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  3. NM_001202466.3 → NP_001189395.1  zinc finger MYND domain-containing protein 11 isoform e

    See identical proteins and their annotated locations for NP_001189395.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variant 24, encodes isoform e.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    UniProtKB/TrEMBL
    B7Z2J6, B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:217 → 298
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 203
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:508 → 543
    zf-MYND; MYND finger

  4. NM_001202467.1 → NP_001189396.1  zinc finger MYND domain-containing protein 11 isoform f

    See identical proteins and their annotated locations for NP_001189396.1

    Status: REVIEWED

    Source sequence(s)
    AI244299, AL589988, BC034784, DB521520, DQ335454
    Consensus CDS
    CCDS91197.1
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000515849.1, ENST00000704335.1
    Conserved Domains (2) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...

  5. NM_001202468.1 → NP_001189397.1  zinc finger MYND domain-containing protein 11 isoform g

    See identical proteins and their annotated locations for NP_001189397.1

    Status: REVIEWED

    Source sequence(s)
    AI244299, AL589988, BC034784, DB521520, DQ335455
    Consensus CDS
    CCDS55696.1
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000452959.1, ENST00000558098.4
    Conserved Domains (3) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69

  6. NM_001330057.3 → NP_001316986.1  zinc finger MYND domain-containing protein 11 isoform h precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variant 25, encodes isoform h.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (4) summary
    cd05841
    Location:255 → 336
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:141 → 241
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:85 → 128
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:546 → 581
    zf-MYND; MYND finger

  7. NM_001370097.3 → NP_001357026.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 1 and 11-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563 → 598
    zf-MYND; MYND finger

  8. NM_001370098.2 → NP_001357027.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 1, 10, and 12-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563 → 598
    zf-MYND; MYND finger

  9. NM_001370099.2 → NP_001357028.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 1, 10, 11, and 13-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000371003.1, ENST00000381591.5
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563 → 598
    zf-MYND; MYND finger

  10. NM_001370100.5 → NP_001357029.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 1, 10-12, 14, and 15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000371017.6, ENST00000381604.9
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563 → 598
    zf-MYND; MYND finger

  11. NM_001370101.2 → NP_001357030.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 1, 10-13, and 15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563 → 598
    zf-MYND; MYND finger

  12. NM_001370102.2 → NP_001357031.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 1 and 10-14, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000515825.1, ENST00000704301.1
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563 → 598
    zf-MYND; MYND finger

  13. NM_001370103.2 → NP_001357032.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 4 and 17-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000515819.1, ENST00000704295.1
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  14. NM_001370104.2 → NP_001357033.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 4, 16, and 18-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  15. NM_001370105.2 → NP_001357034.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variants 4, 16, 17, and 19-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  16. NM_001370106.2 → NP_001357035.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variants 4, 16-18, and 20-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  17. NM_001370107.2 → NP_001357036.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 4, 16-19, 21, and 22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  18. NM_001370108.2 → NP_001357037.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 4, 16-20, and 22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  19. NM_001370109.2 → NP_001357038.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 4 and 16-21, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000515827.1, ENST00000704303.1
    Conserved Domains (3) summary
    cd05841
    Location:218 → 299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509 → 544
    zf-MYND; MYND finger

  20. NM_001370110.2 → NP_001357039.1  zinc finger MYND domain-containing protein 11 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23), as well as variant 5, encodes isoform d.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS55697.1
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000473321.1, ENST00000602682.6
    Conserved Domains (3) summary
    cd05841
    Location:187 → 268
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:478 → 513
    zf-MYND; MYND finger
    cl02556
    Location:95 → 173
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  21. NM_001370111.2 → NP_001357040.1  zinc finger MYND domain-containing protein 11 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variant 6, encodes isoform e.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    UniProtKB/TrEMBL
    B7Z2J6, B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:217 → 298
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104 → 203
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:508 → 543
    zf-MYND; MYND finger

  22. NM_001370112.2 → NP_001357041.1  zinc finger MYND domain-containing protein 11 isoform h precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variant 9, encodes isoform h.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (4) summary
    cd05841
    Location:255 → 336
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:141 → 241
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:85 → 128
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:546 → 581
    zf-MYND; MYND finger

  23. NM_001370113.2 → NP_001357042.1  zinc finger MYND domain-containing protein 11 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variant 27, encodes isoform i.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS91196.1
    UniProtKB/TrEMBL
    B7Z3W2, E7ENI9
    Conserved Domains (3) summary
    cd05841
    Location:241 → 322
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:532 → 567
    zf-MYND; MYND finger
    cl02556
    Location:113 → 227
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  24. NM_001370114.2 → NP_001357043.1  zinc finger MYND domain-containing protein 11 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variant 6, encodes isoform i.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS91196.1
    UniProtKB/TrEMBL
    B7Z3W2, E7ENI9
    Related
    ENSP00000386010.1, ENST00000402736.5
    Conserved Domains (3) summary
    cd05841
    Location:241 → 322
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:532 → 567
    zf-MYND; MYND finger
    cl02556
    Location:113 → 227
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  25. NM_001370115.2 → NP_001357044.1  zinc finger MYND domain-containing protein 11 isoform j

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS91195.1
    UniProtKB/TrEMBL
    A0A0D9SGD6, B7Z3W2
    Related
    ENSP00000487386.2, ENST00000627286.2
    Conserved Domains (4) summary
    cd05841
    Location:271 → 352
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 257
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:562 → 597
    zf-MYND; MYND finger

  26. NM_001370116.2 → NP_001357045.1  zinc finger MYND domain-containing protein 11 isoform k

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (4) summary
    cd05841
    Location:250 → 331
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:136 → 236
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:80 → 123
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:541 → 576
    zf-MYND; MYND finger

  27. NM_001370117.2 → NP_001357046.1  zinc finger MYND domain-containing protein 11 isoform l

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS91194.1
    UniProtKB/TrEMBL
    A0A994J6Y5, B7Z3W2
    Related
    ENSP00000515835.1, ENST00000704315.1
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:540 → 575
    zf-MYND; MYND finger

  28. NM_001370118.2 → NP_001357047.1  zinc finger MYND domain-containing protein 11 isoform m

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    Consensus CDS
    CCDS91199.1
    UniProtKB/TrEMBL
    A0A994J4C0, B7Z3W2
    Related
    ENSP00000515854.1, ENST00000704343.1
    Conserved Domains (4) summary
    cd05841
    Location:232 → 313
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:118 → 218
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:62 → 105
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:523 → 558
    zf-MYND; MYND finger

  29. NM_001370119.2 → NP_001357048.1  zinc finger MYND domain-containing protein 11 isoform n

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    UniProtKB/TrEMBL
    A0A0A0MRY2
    Conserved Domains (4) summary
    cd05841
    Location:252 → 327
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 252
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:514 → 549
    zf-MYND; MYND finger

  30. NM_001370120.2 → NP_001357049.1  zinc finger MYND domain-containing protein 11 isoform o

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    UniProtKB/TrEMBL
    B7Z3W2
    Conserved Domains (3) summary
    cd05841
    Location:196 → 277
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:82 → 182
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:487 → 522
    zf-MYND; MYND finger

  31. NM_001370121.2 → NP_001357050.1  zinc finger MYND domain-containing protein 11 isoform p

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    UniProtKB/TrEMBL
    B7Z3W2, Q5BJG6
    Conserved Domains (3) summary
    cd05841
    Location:178 → 259
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:64 → 164
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:469 → 504
    zf-MYND; MYND finger

  32. NM_001370122.2 → NP_001357051.1  zinc finger MYND domain-containing protein 11 isoform q

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS91198.1
    UniProtKB/TrEMBL
    A0A994J4I8, A0A994J4J2
    Related
    ENSP00000515831.1, ENST00000704307.1
    Conserved Domains (3) summary
    cd05841
    Location:170 → 251
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:461 → 496
    zf-MYND; MYND finger
    cl02556
    Location:104 → 149
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  33. NM_001370123.2 → NP_001357052.1  zinc finger MYND domain-containing protein 11 isoform r precursor

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    UniProtKB/TrEMBL
    A0A0A0MRY2, Q5UGI2
    Conserved Domains (3) summary
    cd05841
    Location:153 → 234
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:444 → 479
    zf-MYND; MYND finger
    cl02556
    Location:87 → 132
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  34. NM_001370124.3 → NP_001357053.1  zinc finger MYND domain-containing protein 11 isoform s

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    UniProtKB/TrEMBL
    B7Z3Z1
    Conserved Domains (3) summary
    cd05841
    Location:115 → 196
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:1 → 101
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:406 → 441
    zf-MYND; MYND finger

  35. NM_006624.7 → NP_006615.2  zinc finger MYND domain-containing protein 11 isoform a

    See identical proteins and their annotated locations for NP_006615.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1), as well as variants 10-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000381053.3, ENST00000397962.8
    Conserved Domains (4) summary
    cd05841
    Location:272 → 353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563 → 598
    zf-MYND; MYND finger

  36. NM_212479.4 → NP_997644.2  zinc finger MYND domain-containing protein 11 isoform b

    See identical proteins and their annotated locations for NP_997644.2

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL713922, AL731539
    Consensus CDS
    CCDS7053.2
    UniProtKB/TrEMBL
    B7Z3W2
    Related
    ENSP00000424205.2, ENST00000509513.6
    Conserved Domains (3) summary
    cd05841
    Location:271 → 352
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158 → 257
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102 → 145
    PHD_BS69; PHD finger found in protein BS69

RNA

  1. NR_163254.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Related
    ENST00000381584.6

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    130088..254637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015594.2 → XP_016871083.1  zinc finger MYND domain-containing protein 11 isoform X1

    UniProtKB/TrEMBL
    B7Z3W2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    122992..247610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054364630.1 → XP_054220605.1  zinc finger MYND domain-containing protein 11 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q15326.2 GenPept UniProtKB/Swiss-Prot:Q15326

Gene LinkOut

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