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Mrpl41 mitochondrial ribosomal protein L41 [ Mus musculus (house mouse) ]

Gene ID: 107733, updated on 5-Mar-2024

Summary

Official Symbol
Mrpl41provided by MGI
Official Full Name
mitochondrial ribosomal protein L41provided by MGI
Primary source
MGI:MGI:1333816
See related
Ensembl:ENSMUSG00000036850 AllianceGenome:MGI:1333816
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpml27; MRP-L27
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to act upstream of or within apoptotic process. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL41 (mitochondrial ribosomal protein L41). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 10.1), CNS E14 (RPKM 10.0) and 28 other tissues See more
Orthologs
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Genomic context

Location:
2 A3; 2 16.88 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (24862482..24865110, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (24972470..24975098, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene zinc finger, MYND domain containing 19 Neighboring gene STARR-positive B cell enhancer ABC_E5898 Neighboring gene diphthamine biosynethesis 7 Neighboring gene STARR-positive B cell enhancer ABC_E1001 Neighboring gene patatin-like phospholipase domain containing 7 Neighboring gene ribosomal protein L21 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Transgenic (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein mL41
Names
39S ribosomal protein L41, mitochondrial
L41mt
MRP-L41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031808.2NP_001026978.2  large ribosomal subunit protein mL41 precursor

    See identical proteins and their annotated locations for NP_001026978.2

    Status: VALIDATED

    Source sequence(s)
    AK003340, AK011837, AK032370, AL732585
    Consensus CDS
    CCDS15744.1
    UniProtKB/Swiss-Prot
    Q8BJ44, Q9CQN7
    Related
    ENSMUSP00000043561.4, ENSMUST00000045604.4
    Conserved Domains (1) summary
    pfam09809
    Location:13125
    MRP-L27; Mitochondrial ribosomal protein L27

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    24862482..24865110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)