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znf408 zinc finger protein 408 [ Danio rerio (zebrafish) ]

Gene ID: 108004540, updated on 5-Jan-2022

Summary

Official Symbol
znf408provided by ZNC
Official Full Name
zinc finger protein 408provided by ZNC
Primary source
ZFIN:ZDB-GENE-130530-589
See related
Ensembl:ENSDARG00000036043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable metal ion binding activity. Acts upstream of or within retina vasculature development in camera-type eye. Predicted to be located in nucleus. Used to study exudative vitreoretinopathy. Human ortholog(s) of this gene implicated in exudative vitreoretinopathy 6 and retinitis pigmentosa 72. Orthologous to human ZNF408 (zinc finger protein 408). [provided by Alliance of Genome Resources, Nov 2021]
Orthologs
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Genomic context

See znf408 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (38744977..38750146)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (38473719..38478888)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene F-box protein 3 Neighboring gene synaptotagmin XIII Neighboring gene coagulation factor II (thrombin) Neighboring gene Rho GTPase activating protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 408
Names
zmp:0000000586

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328275.1NP_001315204.1  zinc finger protein 408

    Status: VALIDATED

    Source sequence(s)
    BX957256
    UniProtKB/TrEMBL
    E7FAN3
    Related
    ENSDARP00000052328.4, ENSDART00000052329.7

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    38744977..38750146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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