rbp7a retinol binding protein 7a, cellular [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rbp7aprovided by ZNC
Official Full Name: retinol binding protein 7a, cellularprovided by ZNC
Primary source: ZFIN:ZDB-GENE-071004-2
See related: Ensembl:ENSDARG00000091906 AllianceGenome:ZFIN:ZDB-GENE-071004-2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable fatty acid binding activity. Acts upstream of or within determination of heart left/right asymmetry and left/right pattern formation. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; marginal blastomere; noninvoluting endocytic marginal cell cluster; and pleuroperitoneal region. Orthologous to human RBP7 (retinol binding protein 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (29554591..29556844, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (29628050..29630303, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results find that early embryonic rbp7a expression is negatively regulated by the Nodal/FoxH1-signaling pathway suggesting a local role of rbp7a in forerunner cells required for the establishment of a left side-specific Nodal activity in the embryo.
Title: Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7.

Submit: New GeneRIF Correction

General gene information

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Readthrough nmnat1-rbp7a

Readthrough gene: nmnat1-rbp7a, Included gene: nmnat1

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables fatty acid binding	IBA Inferred from Biological aspect of Ancestor more info
enables lipid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within determination of heart left/right asymmetry	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within left/right pattern formation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: retinoid-binding protein 7a

Names: rbp7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.