Format

Send to:

Choose Destination

Slco1a5 solute carrier organic anion transporter family, member 1a5 [ Mus musculus (house mouse) ]

Gene ID: 108096, updated on 23-Jun-2021

Summary

Official Symbol
Slco1a5provided by MGI
Official Full Name
solute carrier organic anion transporter family, member 1a5provided by MGI
Primary source
MGI:MGI:1351865
See related
Ensembl:ENSMUSG00000063975
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Oa; Slc2; Oatp3; Oatp-3; Slc21a7
Expression
Biased expression in genital fat pad adult (RPKM 1.3), liver adult (RPKM 0.4) and 9 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Slco1a5 in Genome Data Viewer
Location:
6; 6 G2
Exon count:
16
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (142179953..142268707, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (142234227..142322981, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (142182750..142271470, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene 6614 Neighboring gene solute carrier organic anion transporter family, member 1a6 Neighboring gene predicted gene, 18159 Neighboring gene predicted gene, 53313 Neighboring gene 60S ribosomal protein L18 pseudogene Neighboring gene islet amyloid polypeptide Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene RecQ protein-like Neighboring gene golgi transport 1B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in bile acid and bile salt transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bile acid and bile salt transport ISO
Inferred from Sequence Orthology
more info
 
involved_in intestinal absorption ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in monocarboxylic acid transport ISO
Inferred from Sequence Orthology
more info
 
involved_in organic anion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in brush border membrane ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier organic anion transporter family member 1A5
Names
organic anion-transporting polypeptide 3
sodium-independent organic anion transporter 3
solute carrier family 21 (organic anion transporter), member 7
solute carrier family 21 member 7

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001267707.1NP_001254636.1  solute carrier organic anion transporter family member 1A5

    See identical proteins and their annotated locations for NP_001254636.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC102125, FQ790388
    Consensus CDS
    CCDS57464.1
    UniProtKB/Swiss-Prot
    Q91YY5
    UniProtKB/TrEMBL
    A0A0G2JDD1
    Related
    ENSMUSP00000137607.2, ENSMUST00000111825.10
    Conserved Domains (3) summary
    cd06174
    Location:23397
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:436488
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter
  2. NM_130861.3NP_570931.1  solute carrier organic anion transporter family member 1A5

    See identical proteins and their annotated locations for NP_570931.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK029706
    Consensus CDS
    CCDS57464.1
    UniProtKB/Swiss-Prot
    Q91YY5
    UniProtKB/TrEMBL
    A0A0G2JDD1
    Related
    ENSMUSP00000080116.4, ENSMUST00000081380.10
    Conserved Domains (3) summary
    cd06174
    Location:23397
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:436488
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    142179953..142268707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center