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Gm45871 predicted gene 45871 [ Mus musculus (house mouse) ]

Gene ID: 108168395, updated on 8-Feb-2024

Summary

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Official Symbol
Gm45871provided by MGI
Official Full Name
predicted gene 45871provided by MGI
Primary source
MGI:MGI:5804986
See related
Ensembl:ENSMUSG00000110277 AllianceGenome:MGI:5804986
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 1.8), large intestine adult (RPKM 1.5) and 26 other tissues See more
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Genomic context

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See Gm45871 in Genome Data Viewer
Location:
18 E4; 18
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (90597884..90613788)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (90579760..90593724)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 18280 Neighboring gene STARR-positive B cell enhancer ABC_E7622 Neighboring gene predicted gene, 25418 Neighboring gene thioredoxin-related transmembrane protein 3 Neighboring gene STARR-seq mESC enhancer starr_45308 Neighboring gene STARR-seq mESC enhancer starr_45309

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC108168395

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362365.1 → NP_001349294.1  uncharacterized protein LOC108168395

    Status: VALIDATED

    Source sequence(s)
    AC165266, BC062254
    Consensus CDS
    CCDS89298.1
    UniProtKB/TrEMBL
    A0A1B0GRI9
    Related
    ENSMUSP00000147542.2, ENSMUST00000211710.2
    Conserved Domains (3) summary
    COG5048
    Location:116 → 538
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:134 → 154
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 44
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    90597884..90613788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030250271.2 → XP_030106131.1  uncharacterized protein LOC108168395 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:79 → 501
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:97 → 117
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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