LOC108251801 PAX4 5' regulatory region [Homo sapiens (human)] - Gene

Summary

Gene symbol: LOC108251801
Gene description: PAX4 5' regulatory region
Gene type: biological region
Feature type(s): protein_bind
regulatory: enhancer, promoter
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary: This region encompasses the promoter and 5' pancreatic enhancer of the paired box 4 (PAX4) gene. Binding by hepatocyte nuclear factor family members and pancreatic and duodenal homeobox 1 may stimulate enhancer activity. This region is negatively regulated by binding of Pax4 to sites several kilobase pairs upstream of the transcription start site. [provided by RefSeq, Jun 2016]
Orthologs: mouse all
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Genomic context

Location:: chromosome: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	7	NC_000007.14 (127618059..127623016)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	7	NC_060931.1 (128929752..128934709)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	7	NC_000007.13 (127258113..127263070)

Chromosome 7 - NC_000007.14 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

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General gene information

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.