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Sprr2a2 small proline-rich protein 2A2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 108350059, updated on 29-Feb-2024

Summary

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Official Symbol
Sprr2a2provided by RGD
Official Full Name
small proline-rich protein 2A2provided by RGD
Primary source
RGD:11469006
See related
Ensembl:ENSRNOG00000037341 AllianceGenome:RGD:11469006
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in keratinization. Predicted to be located in cornified envelope. Orthologous to several human genes including SPRR2A (small proline rich protein 2A); SPRR2B (small proline rich protein 2B); and SPRR2E (small proline rich protein 2E). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
2q34
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (180415180..180415485)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (177719576..177719845)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (192147229..192148625)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene loricrin cornified envelope precursor protein Neighboring gene proline rich 9 Neighboring gene small proline-rich protein 2D-like Neighboring gene small proline-rich protein 2D-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of skin epidermis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cornified envelope ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
small proline-rich protein 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    180415180..180415485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039103920.2 → XP_038959848.1  small proline-rich protein 2B

    UniProtKB/TrEMBL
    A6KMR1, D3ZQA8
    Related
    ENSRNOP00000053336.2
Nucleotide Protein Strain
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Gene LinkOut

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