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Nusap1 nucleolar and spindle associated protein 1 [ Mus musculus (house mouse) ]

Gene ID: 108907, updated on 2-Oct-2021

Summary

Official Symbol
Nusap1provided by MGI
Official Full Name
nucleolar and spindle associated protein 1provided by MGI
Primary source
MGI:MGI:2675669
See related
Ensembl:ENSMUSG00000027306
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LNP; ANKT; SAPL; BM037; NuSAP; Q0310; AI481307; AW547774; BB165529; 2610201A12Rik
Expression
Biased expression in liver E14 (RPKM 34.2), liver E14.5 (RPKM 28.2) and 10 other tissues See more
Orthologs
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Genomic context

See Nusap1 in Genome Data Viewer
Location:
2; 2 E5
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (119448779..119480646)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (119618298..119650165)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (119444034..119475896)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene calcineurin-like EF hand protein 1 Neighboring gene Opa interacting protein 5, opposite strand 1 Neighboring gene Opa interacting protein 5 Neighboring gene nuclear encoded rRNA 5S 204 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 1 Neighboring gene H3 histone, family 3C

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in spindle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nucleolar and spindle-associated protein 1
Names
nucleolar protein ANKT

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042652.1NP_001036117.1  nucleolar and spindle-associated protein 1 isoform b

    See identical proteins and their annotated locations for NP_001036117.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame segment, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a.
    Source sequence(s)
    AK042697, AK044819, CD544519
    Consensus CDS
    CCDS38206.1
    UniProtKB/Swiss-Prot
    Q9ERH4
    Related
    ENSMUSP00000028771.8, ENSMUST00000028771.8
    Conserved Domains (1) summary
    pfam16006
    Location:161388
    NUSAP; Nucleolar and spindle-associated protein
  2. NM_133851.3NP_598612.1  nucleolar and spindle-associated protein 1 isoform a

    See identical proteins and their annotated locations for NP_598612.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform a).
    Source sequence(s)
    AK044819, BC100392
    Consensus CDS
    CCDS16605.1
    UniProtKB/Swiss-Prot
    Q9ERH4
    Related
    ENSMUSP00000068713.9, ENSMUST00000068225.15
    Conserved Domains (1) summary
    pfam16006
    Location:170421
    NUSAP; Nucleolar and spindle-associated protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    119448779..119480646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246564.2XP_030102424.1  nucleolar and spindle-associated protein 1 isoform X1

    Conserved Domains (1) summary
    pfam16006
    Location:40269
    NUSAP; Nucleolar and spindle-associated protein
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