Format

Send to:

Choose Destination

Asl argininosuccinate lyase [ Mus musculus (house mouse) ]

Gene ID: 109900, updated on 23-Jun-2021

Summary

Official Symbol
Aslprovided by MGI
Official Full Name
argininosuccinate lyaseprovided by MGI
Primary source
MGI:MGI:88084
See related
Ensembl:ENSMUSG00000025533
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ASAL; 2510006M18Rik
Expression
Biased expression in liver adult (RPKM 129.2), kidney adult (RPKM 88.2) and 11 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Asl in Genome Data Viewer
Location:
5 G1.3; 5 68.37 cM
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (130040099..130053222, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (130011258..130024381, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (130487373..130500201, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene nuclear protein transcriptional regulator 1 like Neighboring gene vitamin K epoxide reductase complex, subunit 1-like 1 Neighboring gene glucuronidase, beta Neighboring gene predicted gene, 40334 Neighboring gene calcitonin gene-related peptide-receptor component protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables argininosuccinate lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables argininosuccinate lyase activity ISO
Inferred from Sequence Orthology
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell body fiber ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in perikaryon ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
argininosuccinate lyase
Names
arginosuccinase
NP_598529.1
XP_006504404.1
XP_036020620.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133768.5NP_598529.1  argininosuccinate lyase

    See identical proteins and their annotated locations for NP_598529.1

    Status: VALIDATED

    Source sequence(s)
    AI325988, AK140160, BY770404
    Consensus CDS
    CCDS51655.1
    UniProtKB/Swiss-Prot
    Q91YI0
    Related
    ENSMUSP00000124274.2, ENSMUST00000161094.8
    Conserved Domains (1) summary
    cd01359
    Location:27459
    Argininosuccinate_lyase; Argininosuccinate lyase (argininosuccinase, ASAL)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    130040099..130053222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164727.1XP_036020620.1  argininosuccinate lyase isoform X2

    Related
    ENSMUSP00000125143.3, ENSMUST00000159096.8
    Conserved Domains (1) summary
    cd01359
    Location:1230
    Argininosuccinate_lyase; Argininosuccinate lyase (argininosuccinase, ASAL)
  2. XM_006504341.5XP_006504404.1  argininosuccinate lyase isoform X1

    See identical proteins and their annotated locations for XP_006504404.1

    UniProtKB/Swiss-Prot
    Q91YI0
    Related
    ENSMUSP00000124579.2, ENSMUST00000160129.8
    Conserved Domains (1) summary
    cd01359
    Location:27459
    Argininosuccinate_lyase; Argininosuccinate lyase (argininosuccinase, ASAL)
Support Center