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Krt7 keratin 7 [ Mus musculus (house mouse) ]

Gene ID: 110310, updated on 27-Jul-2021

Summary

Official Symbol
Krt7provided by MGI
Official Full Name
keratin 7provided by MGI
Primary source
MGI:MGI:96704
See related
Ensembl:ENSMUSG00000023039
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
K7; Krt2-; Krt2-7; D15Wsu77; D15Wsu77e
Expression
Biased expression in bladder adult (RPKM 403.9), placenta adult (RPKM 196.9) and 9 other tissues See more
Orthologs
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Genomic context

See Krt7 in Genome Data Viewer
Location:
15 F1- F2; 15 56.88 cM
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (101310284..101325687)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (101412403..101427806)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (101242834..101258237)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene keratin 80 Neighboring gene predicted gene, 35853 Neighboring gene microRNA 1941 Neighboring gene predicted gene 671 Neighboring gene keratin 87 Neighboring gene keratin 88

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC11625

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 
located_in keratin filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type II cytoskeletal 7
Names
CK-7
Cytokeratin 7
cytokeratin-7
keratin complex 2, basic, gene 7
sarcolectin
type-II keratin Kb7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033073.3NP_149064.1  keratin, type II cytoskeletal 7

    See identical proteins and their annotated locations for NP_149064.1

    Status: VALIDATED

    Source sequence(s)
    AC157583, AK146914, BU755120
    Consensus CDS
    CCDS27851.1
    UniProtKB/Swiss-Prot
    Q9DCV7
    Related
    ENSMUSP00000069900.9, ENSMUST00000068904.9
    Conserved Domains (5) summary
    pfam00038
    Location:84396
    Filament; Intermediate filament protein
    pfam16208
    Location:581
    Keratin_2_head; Keratin type II head
    cd16269
    Location:189200
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:104220
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl23720
    Location:296365
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    101310284..101325687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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