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Lgals3 galectin 3 [ Mus pahari (shrew mouse) ]

Gene ID: 110325787, updated on 15-Mar-2024

Summary

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Gene symbol
Lgals3
Gene description
galectin 3
See related
Ensembl:MGP_PahariEiJ_G0030183
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus pahari
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Coelomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
101 current PAHARI_EIJ_v1.1 (GCF_900095145.1) 8 NC_034597.1 (38198803..38211168)

Chromosome 8 - NC_034597.1Genomic Context describing neighboring genes Neighboring gene WD repeat and HMG-box DNA binding protein 1 Neighboring gene suppressor of cytokine signaling 4 Neighboring gene mitogen-activated protein kinase 1 interacting protein 1 like Neighboring gene DLG associated protein 5 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034597.1 Chromosome 8 Reference PAHARI_EIJ_v1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic deletion of galectin-3 enhances neuroinflammation, affects microglial activation and contributes to sub-chronic injury in experimental neonatal focal stroke. Chip S, et al. Brain Behav Immun, 2017 Feb. PMID 27836669, Free PMC Article
  2. Galectin-3 modulates postnatal subventricular zone gliogenesis. Al-Dalahmah O, et al. Glia, 2020 Feb. PMID 31626379, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. that Gal-3 immunoreactivity was increased in the perinatal human SVZ and striatum after hypoxia/ischemia
    Title: Galectin-3 modulates postnatal subventricular zone gliogenesis.
  2. that lack of Gal3 worsens subchronic injury after neonatal focal stroke
    Title: Genetic deletion of galectin-3 enhances neuroinflammation, affects microglial activation and contributes to sub-chronic injury in experimental neonatal focal stroke.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables IgE binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables laminin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in eosinophil chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in macrophage chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of calcium ion import IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in immunological synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
galectin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus pahari Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PAHARI_EIJ_v1.1

Genomic

  1. NC_034597.1 Reference PAHARI_EIJ_v1.1

    Range
    38198803..38211168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021203896.2 → XP_021059555.1  galectin-3

    Related
    MGP_PahariEiJ_P0084469, MGP_PahariEiJ_T0084469.1
    Conserved Domains (2) summary
    smart00908
    Location:137 → 258
    Gal-bind_lectin; Galactoside-binding lectin
    cl26386
    Location:9 → 139
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  2. XM_021203895.2 → XP_021059554.1  galectin-3

    Related
    MGP_PahariEiJ_P0084470, MGP_PahariEiJ_T0084470.1
    Conserved Domains (2) summary
    smart00908
    Location:137 → 258
    Gal-bind_lectin; Galactoside-binding lectin
    cl26386
    Location:9 → 139
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
Nucleotide Protein
Heading Accession and Version

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