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LOC111242786 MID1 promoter D [ Homo sapiens (human) ]

Gene ID: 111242786, updated on 10-Oct-2023

Summary

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Gene symbol
LOC111242786
Gene description
MID1 promoter D
Gene type
biological region
Feature type(s)
mobile_element
regulatory: enhancer, promoter
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This region represents an endogenous retrovirus long terminal repeat (LTR) element that functions as an alternate promoter of the midline 1 (MID1) gene. This sequence can act as both an enhancer and a promoter in a placental cell line. [provided by RefSeq, Oct 2017]
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Genomic context

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See LOC111242786 in Genome Data Viewer
Location:
chromosome: X
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (10589855..10590337)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (10172378..10172860)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (10557895..10558377)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:10141885-10142861 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20656 Neighboring gene chloride voltage-gated channel 4 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:10416979-10418178 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:10476778-10477647 Neighboring gene midline 1 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:10539598-10539816 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:10579147-10580022 Neighboring gene uncharacterized LOC124905245 Neighboring gene RNA, U6 small nuclear 800, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chrX:10602208-10603407 Neighboring gene Sharpr-MPRA regulatory region 5514 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20657 Neighboring gene uncharacterized LOC124905244 Neighboring gene HCCS divergent transcript Neighboring gene Sharpr-MPRA regulatory region 6238

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Opitz syndrome gene Mid1 is transcribed from a human endogenous retroviral promoter. Landry JR, et al. Mol Biol Evol, 2002 Nov. PMID 12411602
  2. Widely spaced alternative promoters, conserved between human and rodent, control expression of the Opitz syndrome gene MID1. Landry JR, et al. Genomics, 2002 Nov. PMID 12408967
  3. Characterization and physical mapping in human and mouse of a novel RING finger gene in Xp22. Van den Veyver IB, et al. Genomics, 1998 Jul 15. PMID 9722948
  4. Endogenous retroviral LTRs as promoters for human genes: a critical assessment. Cohen CJ, et al. Gene, 2009 Dec 15. PMID 19577618

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

General gene information

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Other Names

  • MID1 LTR promoter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_055593.1 

    Range
    101..583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    10589855..10590337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    10172378..10172860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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