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LOC112163552 Sharpr-MPRA regulatory region 2870 [ Homo sapiens (human) ]

Gene ID: 112163552, updated on 23-Nov-2021

Summary

Gene symbol
LOC112163552
Gene description
Sharpr-MPRA regulatory region 2870
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in HepG2 liver carcinoma cells (group: HepG2 Activating DNase matched - State 7:EnhWF, candidate/poised weak enhancer; flanking open chromatin of candidate enhancers). [provided by RefSeq, Mar 2018]
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Genomic context

See LOC112163552 in Genome Data Viewer
Location:
12p
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (4486143..4486437)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (4595309..4595603)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 23 Neighboring gene fibroblast growth factor 6 Neighboring gene chromosome 12 open reading frame 4 Neighboring gene RAD51 associated protein 1

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_056576.1 

    Range
    101..395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    4486143..4486437
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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